Embryo Screening for Polygenic Disease Risk: Recent Advances and Ethical Considerations
Machine learning methods applied to large genomic datasets (such as those used in GWAS) have led to the creation of polygenic risk scores (PRSs) that can be used identify individuals who are at highly elevated risk for important disease conditions, such as coronary artery disease (CAD), diabetes, hy...
Main Authors: | Laurent C. A. M. Tellier, Jennifer Eccles, Nathan R. Treff, Louis Lello, Simon Fishel, Stephen Hsu |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-07-01
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Series: | Genes |
Subjects: | |
Online Access: | https://www.mdpi.com/2073-4425/12/8/1105 |
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