Less Reactive Thiol Ligands: Key towards Highly Mucoadhesive Drug Delivery Systems

Less Reactive Thiol Ligands: Key towards Highly Mucoadhesive Drug Delivery Systems

As less reactive <span style="font-variant: small-caps;">s</span>-protected thiomers can likely interpenetrate the mucus gel layer to a higher extent before getting immobilized via disulfide bond formation with mucins, it was the aim of this study to develop a novel type of <...

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Bibliographic Details
Main Authors: Iram Shahzadi, Andrea Fürst, Zeynep Burcu Akkus-Dagdeviren, Shumaila Arshad, Markus Kurpiers, Barbara Matuszczak, Andreas Bernkop-Schnürch
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Polymers
Subjects:
less reactive thiomers
mucoadhesion
mucus diffusion
polyacrylic acid
<span style="font-variant: small-caps">s</span>-protected thiomers
thiolation
Online Access:https://www.mdpi.com/2073-4360/12/6/1259

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https://www.mdpi.com/2073-4360/12/6/1259

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