Association between hormonal therapy and craniofacial development in subjects between 10 and 18 years of age. Systematic review

Background: Hormone deficiency could affect craniofacial complex during esqueletal growth and development. Objective: Determine whether there is scientific evidence of the association between hormonal treatment and craniofacial growth measured by cephalometry films, in subjects of 10 to 18 years...

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Main Authors: Juliana Isabel Ceballos, Sebastián Pineda, Zulma Vanesa Rueda, María Clara Lema, Natalia Johnson
Format: Article
Language:Spanish
Published: Universidad del Valle 2017-09-01
Series:Revista Estomatologâia
Subjects:
Online Access:https://entornogeografico.univalle.edu.co/index.php/revista_estomatologia/article/view/5779
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author Juliana Isabel Ceballos
Sebastián Pineda
Zulma Vanesa Rueda
María Clara Lema
Natalia Johnson
author_facet Juliana Isabel Ceballos
Sebastián Pineda
Zulma Vanesa Rueda
María Clara Lema
Natalia Johnson
author_sort Juliana Isabel Ceballos
collection DOAJ
description Background: Hormone deficiency could affect craniofacial complex during esqueletal growth and development. Objective: Determine whether there is scientific evidence of the association between hormonal treatment and craniofacial growth measured by cephalometry films, in subjects of 10 to 18 years with hormonal treatment. Materials and Methods: A systematic review. For the articles published in PubMed, Google Scholar, Lilacs, Embase and Science Direct databases, without restriction of publication year was performed. Clinical trials, case control studies, cohort, systematic reviews and meta analysis studies were included. Reading f the abstracts and the complete articles were made by two researchers. Results: Among 1085 articles found, 1074 were excluded because did not meet the inclusion criteria. After complete reading of the articles, five were excluded because they were cross-sectional studies and one was not recovered in the full text. In total, 6 articles were included. These studies report that patients who were treated with hormone substitution therapy showed favorable changes in their craniofacial structures, especially in mandibular total length, ramus length and mandibular body length. These positive changes led to an improvement in profile, inter-maxillary relations, and other osseous body structures. Conclusions: Despite the heterogeneity of the studies it was found that early replacement with hormone treatment, regardless of the dose and long-term treatment, accelerates the development of craniofacial structures, mainly the mandible, to reach the skeletal patterns genetically established. Studies are required to evaluate replacehormone treatment in patients without additional systemic compromises.  
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spelling doaj.art-8a15c7ed9f904550b341e68641fbfc0c2024-02-10T01:43:49ZspaUniversidad del ValleRevista Estomatologâia0121-38732248-72202017-09-0122210.25100/re.v22i2.5779Association between hormonal therapy and craniofacial development in subjects between 10 and 18 years of age. Systematic reviewJuliana Isabel CeballosSebastián PinedaZulma Vanesa RuedaMaría Clara LemaNatalia Johnson Background: Hormone deficiency could affect craniofacial complex during esqueletal growth and development. Objective: Determine whether there is scientific evidence of the association between hormonal treatment and craniofacial growth measured by cephalometry films, in subjects of 10 to 18 years with hormonal treatment. Materials and Methods: A systematic review. For the articles published in PubMed, Google Scholar, Lilacs, Embase and Science Direct databases, without restriction of publication year was performed. Clinical trials, case control studies, cohort, systematic reviews and meta analysis studies were included. Reading f the abstracts and the complete articles were made by two researchers. Results: Among 1085 articles found, 1074 were excluded because did not meet the inclusion criteria. After complete reading of the articles, five were excluded because they were cross-sectional studies and one was not recovered in the full text. In total, 6 articles were included. These studies report that patients who were treated with hormone substitution therapy showed favorable changes in their craniofacial structures, especially in mandibular total length, ramus length and mandibular body length. These positive changes led to an improvement in profile, inter-maxillary relations, and other osseous body structures. Conclusions: Despite the heterogeneity of the studies it was found that early replacement with hormone treatment, regardless of the dose and long-term treatment, accelerates the development of craniofacial structures, mainly the mandible, to reach the skeletal patterns genetically established. Studies are required to evaluate replacehormone treatment in patients without additional systemic compromises.   https://entornogeografico.univalle.edu.co/index.php/revista_estomatologia/article/view/5779Hormonesgrowth and developmentcraniofacial disorderscephalometrymandibledeficiency
spellingShingle Juliana Isabel Ceballos
Sebastián Pineda
Zulma Vanesa Rueda
María Clara Lema
Natalia Johnson
Association between hormonal therapy and craniofacial development in subjects between 10 and 18 years of age. Systematic review
Revista Estomatologâia
Hormones
growth and development
craniofacial disorders
cephalometry
mandible
deficiency
title Association between hormonal therapy and craniofacial development in subjects between 10 and 18 years of age. Systematic review
title_full Association between hormonal therapy and craniofacial development in subjects between 10 and 18 years of age. Systematic review
title_fullStr Association between hormonal therapy and craniofacial development in subjects between 10 and 18 years of age. Systematic review
title_full_unstemmed Association between hormonal therapy and craniofacial development in subjects between 10 and 18 years of age. Systematic review
title_short Association between hormonal therapy and craniofacial development in subjects between 10 and 18 years of age. Systematic review
title_sort association between hormonal therapy and craniofacial development in subjects between 10 and 18 years of age systematic review
topic Hormones
growth and development
craniofacial disorders
cephalometry
mandible
deficiency
url https://entornogeografico.univalle.edu.co/index.php/revista_estomatologia/article/view/5779
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