α-Glucosidase and α-Amylase Inhibitory Potentials of Quinoline–1,3,4-oxadiazole Conjugates Bearing 1,2,3-Triazole with Antioxidant Activity, Kinetic Studies, and Computational Validation

α-Glucosidase and α-Amylase Inhibitory Potentials of Quinoline–1,3,4-oxadiazole Conjugates Bearing 1,2,3-Triazole with Antioxidant Activity, Kinetic Studies, and Computational Validation

Diabetes mellitus (DM) is a multifaceted metabolic disorder that remains a major threat to global health security. Sadly, the clinical relevance of available drugs is burdened with an upsurge in adverse effects; hence, inhibiting the carbohydrate-hydrolyzing enzymes α-glucosidase and α-amylase while...

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Bibliographic Details
Main Authors:	Nosipho Cele, Paul Awolade, Pule Seboletswe, Kolawole Olofinsan, Md. Shahidul Islam, Parvesh Singh
Format:	Article
Language:	English
Published:	MDPI AG 2022-08-01
Series:	Pharmaceuticals
Subjects:	quinoline 1,3,4-oxadiazole 1,2,3-triazole α-glucosidase inhibitor enzyme kinetics molecular dynamics
Online Access:	https://www.mdpi.com/1424-8247/15/8/1035

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