The recent development and applications of fluidic channels by 3D printing
Abstract The technology of “Lab-on-a-Chip” allows the synthesis and analysis of chemicals and biological substance within a portable or handheld device. The 3D printed structures enable precise control of various geometries. The combination of these two technologies in recent years makes a significa...
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| Format: | Article |
| Language: | English |
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BMC
2017-10-01
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| Series: | Journal of Biomedical Science |
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| Online Access: | http://link.springer.com/article/10.1186/s12929-017-0384-2 |
| _version_ | 1818507745702182912 |
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| author | Yufeng Zhou |
| author_facet | Yufeng Zhou |
| author_sort | Yufeng Zhou |
| collection | DOAJ |
| description | Abstract The technology of “Lab-on-a-Chip” allows the synthesis and analysis of chemicals and biological substance within a portable or handheld device. The 3D printed structures enable precise control of various geometries. The combination of these two technologies in recent years makes a significant progress. The current approaches of 3D printing, such as stereolithography, polyjet, and fused deposition modeling, are introduced. Their manufacture specifications, such as surface roughness, resolution, replication fidelity, cost, and fabrication time, are compared with each other. Finally, novel application of 3D printed channel in biology are reviewed, including pathogenic bacteria detection using magnetic nanoparticle clusters in a helical microchannel, cell stimulation by 3D chemical gradients, perfused functional vascular channels, 3D tissue construct, organ-on-a-chip, and miniaturized fluidic “reactionware” devices for chemical syntheses. Overall, the 3D printed fluidic chip is becoming a powerful tool in the both medical and chemical industries. |
| first_indexed | 2024-12-10T22:22:16Z |
| format | Article |
| id | doaj.art-8a1a6fb7b8d441b3906986e83302110b |
| institution | Directory Open Access Journal |
| issn | 1423-0127 |
| language | English |
| last_indexed | 2024-12-10T22:22:16Z |
| publishDate | 2017-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Biomedical Science |
| spelling | doaj.art-8a1a6fb7b8d441b3906986e83302110b2022-12-22T01:31:16ZengBMCJournal of Biomedical Science1423-01272017-10-0124112210.1186/s12929-017-0384-2The recent development and applications of fluidic channels by 3D printingYufeng Zhou0Singapore Centre for 3D Printing (SC3DP), School of Mechanical and Aerospace Engineering, Nanyang Technological UniversityAbstract The technology of “Lab-on-a-Chip” allows the synthesis and analysis of chemicals and biological substance within a portable or handheld device. The 3D printed structures enable precise control of various geometries. The combination of these two technologies in recent years makes a significant progress. The current approaches of 3D printing, such as stereolithography, polyjet, and fused deposition modeling, are introduced. Their manufacture specifications, such as surface roughness, resolution, replication fidelity, cost, and fabrication time, are compared with each other. Finally, novel application of 3D printed channel in biology are reviewed, including pathogenic bacteria detection using magnetic nanoparticle clusters in a helical microchannel, cell stimulation by 3D chemical gradients, perfused functional vascular channels, 3D tissue construct, organ-on-a-chip, and miniaturized fluidic “reactionware” devices for chemical syntheses. Overall, the 3D printed fluidic chip is becoming a powerful tool in the both medical and chemical industries.http://link.springer.com/article/10.1186/s12929-017-0384-2Fluidic channelLab-on-a-chip3D printingDiagnosisTissue engineeringReactionware |
| spellingShingle | Yufeng Zhou The recent development and applications of fluidic channels by 3D printing Journal of Biomedical Science Fluidic channel Lab-on-a-chip 3D printing Diagnosis Tissue engineering Reactionware |
| title | The recent development and applications of fluidic channels by 3D printing |
| title_full | The recent development and applications of fluidic channels by 3D printing |
| title_fullStr | The recent development and applications of fluidic channels by 3D printing |
| title_full_unstemmed | The recent development and applications of fluidic channels by 3D printing |
| title_short | The recent development and applications of fluidic channels by 3D printing |
| title_sort | recent development and applications of fluidic channels by 3d printing |
| topic | Fluidic channel Lab-on-a-chip 3D printing Diagnosis Tissue engineering Reactionware |
| url | http://link.springer.com/article/10.1186/s12929-017-0384-2 |
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