Fibrosarcoma of the Mandible: A Diagnostic Dilemma

Fibrosarcoma is a malignant mesenchymal neoplasm of fibroblasts that rarely affects oral cavity and can cause local recurrences or metastasis. The aetiologic factors are still unknown, but many authors have reported the radiation therapy history as an important aetiological factor, followed by tra...

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Main Authors: Kanwar Deep Singh Nanda, Anurag Mehta, Jasmine Nanda
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2013-08-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/3295/89-%205608_PF1(M)_E(C)_F(T)_PF1(V)_PF1(T)_PFA(PR)_PF3_(PUH)_B.pdf
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author Kanwar Deep Singh Nanda
Anurag Mehta
Jasmine Nanda
author_facet Kanwar Deep Singh Nanda
Anurag Mehta
Jasmine Nanda
author_sort Kanwar Deep Singh Nanda
collection DOAJ
description Fibrosarcoma is a malignant mesenchymal neoplasm of fibroblasts that rarely affects oral cavity and can cause local recurrences or metastasis. The aetiologic factors are still unknown, but many authors have reported the radiation therapy history as an important aetiological factor, followed by trauma and underlying conditions like Paget’s disease, fibrous dysplasia or chronic osteomyelitis. Fibrosarcoma of mandible is rare, with an incidence which ranges from 0-6.1% of all primary fibrosarcomas of the bone. This paper has described a case of a swelling in the mandible of a 17-years old female who had a radiolucency in association with crown of an impacted tooth and foci of radiopacity, which led to a misdiagnosis of either an odontogenic lesion or a bone tumour, but proved to be a fibrosarcoma on histopathological and immunohistochemistry investigations.
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spelling doaj.art-8a1a9c7372bd422fa6913e3fe8f07c2a2022-12-21T19:04:56ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2013-08-01781804180510.7860/JCDR/2013/5608.3295Fibrosarcoma of the Mandible: A Diagnostic DilemmaKanwar Deep Singh Nanda0Anurag Mehta1Jasmine Nanda2Senior Lecturer, Department of Oral and Maxillofacial Pathology, SGT Dental and Medical College, Gurgaon, India.Head of Pathology, Department of Pathology, Rajiv Gandhi Cancer Institute and Research Institute, Rohini, India.Post Graduate Student, ITS Dental College, Muradabad, Uttar Pradesh, India.Fibrosarcoma is a malignant mesenchymal neoplasm of fibroblasts that rarely affects oral cavity and can cause local recurrences or metastasis. The aetiologic factors are still unknown, but many authors have reported the radiation therapy history as an important aetiological factor, followed by trauma and underlying conditions like Paget’s disease, fibrous dysplasia or chronic osteomyelitis. Fibrosarcoma of mandible is rare, with an incidence which ranges from 0-6.1% of all primary fibrosarcomas of the bone. This paper has described a case of a swelling in the mandible of a 17-years old female who had a radiolucency in association with crown of an impacted tooth and foci of radiopacity, which led to a misdiagnosis of either an odontogenic lesion or a bone tumour, but proved to be a fibrosarcoma on histopathological and immunohistochemistry investigations.https://jcdr.net/articles/PDF/3295/89-%205608_PF1(M)_E(C)_F(T)_PF1(V)_PF1(T)_PFA(PR)_PF3_(PUH)_B.pdffibrosarcomamandiblevimentinspindle cell tumourmisdiagnosisoral cavity
spellingShingle Kanwar Deep Singh Nanda
Anurag Mehta
Jasmine Nanda
Fibrosarcoma of the Mandible: A Diagnostic Dilemma
Journal of Clinical and Diagnostic Research
fibrosarcoma
mandible
vimentin
spindle cell tumour
misdiagnosis
oral cavity
title Fibrosarcoma of the Mandible: A Diagnostic Dilemma
title_full Fibrosarcoma of the Mandible: A Diagnostic Dilemma
title_fullStr Fibrosarcoma of the Mandible: A Diagnostic Dilemma
title_full_unstemmed Fibrosarcoma of the Mandible: A Diagnostic Dilemma
title_short Fibrosarcoma of the Mandible: A Diagnostic Dilemma
title_sort fibrosarcoma of the mandible a diagnostic dilemma
topic fibrosarcoma
mandible
vimentin
spindle cell tumour
misdiagnosis
oral cavity
url https://jcdr.net/articles/PDF/3295/89-%205608_PF1(M)_E(C)_F(T)_PF1(V)_PF1(T)_PFA(PR)_PF3_(PUH)_B.pdf
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