Mathematical modeling reveals differential dynamics of insulin action models on glycerol and glucose in adolescent girls with obesity

Mathematical modeling reveals differential dynamics of insulin action models on glycerol and glucose in adolescent girls with obesity

Under healthy conditions, the pancreas responds to a glucose challenge by releasing insulin. Insulin suppresses lipolysis in adipose tissue, thereby decreasing plasma glycerol concentration, and it regulates plasma glucose concentration through action in muscle and liver. Insulin resistance (IR) occ...

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Bibliographic Details
Main Authors:	Griffin S. Hampton, Kai Bartlette, Kristen J. Nadeau, Melanie Cree-Green, Cecilia Diniz Behn
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-08-01
Series:	Frontiers in Physiology
Subjects:	glycerol glucose insulin insulin resisitance lipolysis mathematical model
Online Access:	https://www.frontiersin.org/articles/10.3389/fphys.2022.895118/full

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