Nanotechnology: a valuable strategy to improve bacteriocin formulations

Bacteriocins are proteinaceous antibacterial compounds, produced by diverse bacteria, which have been successfully used as: (i) food biopreservative; (ii) anti biofilm agents; and (iii) additives or alternatives to the currently existing antibiotics, to minimize the risk of emergence of resistant st...

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Main Authors: Hazem Ahmed Fahim, Ahmed Samir Khairalla, Ahmed Osama El-Gendy
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-09-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01385/full
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author Hazem Ahmed Fahim
Ahmed Samir Khairalla
Ahmed Osama El-Gendy
author_facet Hazem Ahmed Fahim
Ahmed Samir Khairalla
Ahmed Osama El-Gendy
author_sort Hazem Ahmed Fahim
collection DOAJ
description Bacteriocins are proteinaceous antibacterial compounds, produced by diverse bacteria, which have been successfully used as: (i) food biopreservative; (ii) anti biofilm agents; and (iii) additives or alternatives to the currently existing antibiotics, to minimize the risk of emergence of resistant strains. However, there are several limitations that challenge the use of bacteriocins as biopreservatives / antibacterial agents. One of the most promising avenues to overcome these limitations is the use of nanoformulations. This review highlights the practical difficulties with using bacteriocins to control pathogenic microorganisms, and provides an overview on the role of nanotechnology in improving the antimicrobial activity and the physicochemical properties of these peptides.
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spelling doaj.art-8a20440344cd402183cbf43e4a202e5f2022-12-22T00:10:04ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2016-09-01710.3389/fmicb.2016.01385216989Nanotechnology: a valuable strategy to improve bacteriocin formulationsHazem Ahmed Fahim0Ahmed Samir Khairalla1Ahmed Osama El-Gendy2Researcher at the department of Biotechnology and Life Sciences – Faculty of Post Graduate Studies for Advanced Sciences, Beni-Suef University, EgyptLecturer in the department of Microbiology and Immunology - Faculty of Pharmacy- Beni-Suef UniversityLecturer in the department of Microbiology and Immunology - Faculty of Pharmacy- Beni-Suef UniversityBacteriocins are proteinaceous antibacterial compounds, produced by diverse bacteria, which have been successfully used as: (i) food biopreservative; (ii) anti biofilm agents; and (iii) additives or alternatives to the currently existing antibiotics, to minimize the risk of emergence of resistant strains. However, there are several limitations that challenge the use of bacteriocins as biopreservatives / antibacterial agents. One of the most promising avenues to overcome these limitations is the use of nanoformulations. This review highlights the practical difficulties with using bacteriocins to control pathogenic microorganisms, and provides an overview on the role of nanotechnology in improving the antimicrobial activity and the physicochemical properties of these peptides.http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01385/fullBacteriocinsDrug Delivery SystemsNanotechnologyantimicrobial peptidesBiopreservativeNanoformulated bacteriocins
spellingShingle Hazem Ahmed Fahim
Ahmed Samir Khairalla
Ahmed Osama El-Gendy
Nanotechnology: a valuable strategy to improve bacteriocin formulations
Frontiers in Microbiology
Bacteriocins
Drug Delivery Systems
Nanotechnology
antimicrobial peptides
Biopreservative
Nanoformulated bacteriocins
title Nanotechnology: a valuable strategy to improve bacteriocin formulations
title_full Nanotechnology: a valuable strategy to improve bacteriocin formulations
title_fullStr Nanotechnology: a valuable strategy to improve bacteriocin formulations
title_full_unstemmed Nanotechnology: a valuable strategy to improve bacteriocin formulations
title_short Nanotechnology: a valuable strategy to improve bacteriocin formulations
title_sort nanotechnology a valuable strategy to improve bacteriocin formulations
topic Bacteriocins
Drug Delivery Systems
Nanotechnology
antimicrobial peptides
Biopreservative
Nanoformulated bacteriocins
url http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01385/full
work_keys_str_mv AT hazemahmedfahim nanotechnologyavaluablestrategytoimprovebacteriocinformulations
AT ahmedsamirkhairalla nanotechnologyavaluablestrategytoimprovebacteriocinformulations
AT ahmedosamaelgendy nanotechnologyavaluablestrategytoimprovebacteriocinformulations