Nanotechnology: a valuable strategy to improve bacteriocin formulations
Bacteriocins are proteinaceous antibacterial compounds, produced by diverse bacteria, which have been successfully used as: (i) food biopreservative; (ii) anti biofilm agents; and (iii) additives or alternatives to the currently existing antibiotics, to minimize the risk of emergence of resistant st...
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Format: | Article |
Language: | English |
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Frontiers Media S.A.
2016-09-01
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Series: | Frontiers in Microbiology |
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Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01385/full |
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author | Hazem Ahmed Fahim Ahmed Samir Khairalla Ahmed Osama El-Gendy |
author_facet | Hazem Ahmed Fahim Ahmed Samir Khairalla Ahmed Osama El-Gendy |
author_sort | Hazem Ahmed Fahim |
collection | DOAJ |
description | Bacteriocins are proteinaceous antibacterial compounds, produced by diverse bacteria, which have been successfully used as: (i) food biopreservative; (ii) anti biofilm agents; and (iii) additives or alternatives to the currently existing antibiotics, to minimize the risk of emergence of resistant strains. However, there are several limitations that challenge the use of bacteriocins as biopreservatives / antibacterial agents. One of the most promising avenues to overcome these limitations is the use of nanoformulations. This review highlights the practical difficulties with using bacteriocins to control pathogenic microorganisms, and provides an overview on the role of nanotechnology in improving the antimicrobial activity and the physicochemical properties of these peptides. |
first_indexed | 2024-12-12T22:15:49Z |
format | Article |
id | doaj.art-8a20440344cd402183cbf43e4a202e5f |
institution | Directory Open Access Journal |
issn | 1664-302X |
language | English |
last_indexed | 2024-12-12T22:15:49Z |
publishDate | 2016-09-01 |
publisher | Frontiers Media S.A. |
record_format | Article |
series | Frontiers in Microbiology |
spelling | doaj.art-8a20440344cd402183cbf43e4a202e5f2022-12-22T00:10:04ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2016-09-01710.3389/fmicb.2016.01385216989Nanotechnology: a valuable strategy to improve bacteriocin formulationsHazem Ahmed Fahim0Ahmed Samir Khairalla1Ahmed Osama El-Gendy2Researcher at the department of Biotechnology and Life Sciences – Faculty of Post Graduate Studies for Advanced Sciences, Beni-Suef University, EgyptLecturer in the department of Microbiology and Immunology - Faculty of Pharmacy- Beni-Suef UniversityLecturer in the department of Microbiology and Immunology - Faculty of Pharmacy- Beni-Suef UniversityBacteriocins are proteinaceous antibacterial compounds, produced by diverse bacteria, which have been successfully used as: (i) food biopreservative; (ii) anti biofilm agents; and (iii) additives or alternatives to the currently existing antibiotics, to minimize the risk of emergence of resistant strains. However, there are several limitations that challenge the use of bacteriocins as biopreservatives / antibacterial agents. One of the most promising avenues to overcome these limitations is the use of nanoformulations. This review highlights the practical difficulties with using bacteriocins to control pathogenic microorganisms, and provides an overview on the role of nanotechnology in improving the antimicrobial activity and the physicochemical properties of these peptides.http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01385/fullBacteriocinsDrug Delivery SystemsNanotechnologyantimicrobial peptidesBiopreservativeNanoformulated bacteriocins |
spellingShingle | Hazem Ahmed Fahim Ahmed Samir Khairalla Ahmed Osama El-Gendy Nanotechnology: a valuable strategy to improve bacteriocin formulations Frontiers in Microbiology Bacteriocins Drug Delivery Systems Nanotechnology antimicrobial peptides Biopreservative Nanoformulated bacteriocins |
title | Nanotechnology: a valuable strategy to improve bacteriocin formulations |
title_full | Nanotechnology: a valuable strategy to improve bacteriocin formulations |
title_fullStr | Nanotechnology: a valuable strategy to improve bacteriocin formulations |
title_full_unstemmed | Nanotechnology: a valuable strategy to improve bacteriocin formulations |
title_short | Nanotechnology: a valuable strategy to improve bacteriocin formulations |
title_sort | nanotechnology a valuable strategy to improve bacteriocin formulations |
topic | Bacteriocins Drug Delivery Systems Nanotechnology antimicrobial peptides Biopreservative Nanoformulated bacteriocins |
url | http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.01385/full |
work_keys_str_mv | AT hazemahmedfahim nanotechnologyavaluablestrategytoimprovebacteriocinformulations AT ahmedsamirkhairalla nanotechnologyavaluablestrategytoimprovebacteriocinformulations AT ahmedosamaelgendy nanotechnologyavaluablestrategytoimprovebacteriocinformulations |