Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region
The results of retrospective analysis of hemorrhagic fever with renal syndrome (HFRS) incidence in the Perm region for 1995–2009 are shown in the article. There are highly active natural foci of infection on the territory of the region, mainly in the subzone of mixed coniferous-deciduous forests. Fa...
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| Format: | Article |
| Language: | Russian |
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Journal Infectology
2014-09-01
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| Series: | Журнал инфектологии |
| Subjects: | |
| Online Access: | https://journal.niidi.ru/jofin/article/view/44 |
| _version_ | 1797695576462065664 |
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| author | M. V. Ivanova N. N. Vorob’ova K. V. Shmagel A. M. Malkova A. A. Kostarev |
| author_facet | M. V. Ivanova N. N. Vorob’ova K. V. Shmagel A. M. Malkova A. A. Kostarev |
| author_sort | M. V. Ivanova |
| collection | DOAJ |
| description | The results of retrospective analysis of hemorrhagic fever with renal syndrome (HFRS) incidence in the Perm region for 1995–2009 are shown in the article. There are highly active natural foci of infection on the territory of the region, mainly in the subzone of mixed coniferous-deciduous forests. Factors supporting the morbidity are high numbers of small mammals, in particular, the bank vole, with a large circulation of the HFRS virus and active population visit of natural foci in summer-autumn period. Analysis of clinical features of HFRS in 338 patients living in the Perm region, revealed some peculiarities of its course. Among surveyed contingent men (72,4%) prevailed. Most of the patients (80,4%) were of working age (16 to 60 years). More frequently mild and moderate forms (92,8%) of HFRS were observed. A typical picture of the disease with the development of all specific syndromes occurred mainly in patients with severe and moderate forms. Mild cases occurred blurry in the absence of pathognomonic symptoms. Notable was the frequent lesion of liver, with the development of acute anicteric hepatitis (51,2%). Among the complications dominated: pneumonia (4,7%) and acute renal ailure (4,4%). Manifestations of DIC syndrome with recurrent bleeding were registered in 0,6% of patients, toxic shock – at 0,3%. Case fatality rate was 0,6%. |
| first_indexed | 2024-03-12T03:13:20Z |
| format | Article |
| id | doaj.art-8a20626af8a84b41a7ea8a67af1cc498 |
| institution | Directory Open Access Journal |
| issn | 2072-6732 |
| language | Russian |
| last_indexed | 2024-03-12T03:13:20Z |
| publishDate | 2014-09-01 |
| publisher | Journal Infectology |
| record_format | Article |
| series | Журнал инфектологии |
| spelling | doaj.art-8a20626af8a84b41a7ea8a67af1cc4982023-09-03T14:15:27ZrusJournal InfectologyЖурнал инфектологии2072-67322014-09-0133667310.22625/2072-6732-2011-3-3-66-7358Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm regionM. V. Ivanova0N. N. Vorob’ova1K. V. Shmagel2A. M. Malkova3A. A. Kostarev4Пермская государственная медицинская академия им. акад. Е.А. Вагнера, Пермь Краевая клиническая инфекционная больница, ПермьПермская государственная медицинская академия им. акад. Е.А. Вагнера, ПермьПермская государственная медицинская академия им. акад. Е.А. Вагнера, Пермь Институт экологии и генетики микроорганизмов УрО РАН, ПермьУправление федеральной службы по надзору в сфере защиты прав потребителей и благополучия человека по Пермскому краю, ПермьЦентр гигиены и эпидемиологии в Пермском крае, ПермьThe results of retrospective analysis of hemorrhagic fever with renal syndrome (HFRS) incidence in the Perm region for 1995–2009 are shown in the article. There are highly active natural foci of infection on the territory of the region, mainly in the subzone of mixed coniferous-deciduous forests. Factors supporting the morbidity are high numbers of small mammals, in particular, the bank vole, with a large circulation of the HFRS virus and active population visit of natural foci in summer-autumn period. Analysis of clinical features of HFRS in 338 patients living in the Perm region, revealed some peculiarities of its course. Among surveyed contingent men (72,4%) prevailed. Most of the patients (80,4%) were of working age (16 to 60 years). More frequently mild and moderate forms (92,8%) of HFRS were observed. A typical picture of the disease with the development of all specific syndromes occurred mainly in patients with severe and moderate forms. Mild cases occurred blurry in the absence of pathognomonic symptoms. Notable was the frequent lesion of liver, with the development of acute anicteric hepatitis (51,2%). Among the complications dominated: pneumonia (4,7%) and acute renal ailure (4,4%). Manifestations of DIC syndrome with recurrent bleeding were registered in 0,6% of patients, toxic shock – at 0,3%. Case fatality rate was 0,6%.https://journal.niidi.ru/jofin/article/view/44геморрагическая лихорадка с почечным синдромомзаболеваемостьособенности клинического теченияпермский край |
| spellingShingle | M. V. Ivanova N. N. Vorob’ova K. V. Shmagel A. M. Malkova A. A. Kostarev Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region Журнал инфектологии геморрагическая лихорадка с почечным синдромом заболеваемость особенности клинического течения пермский край |
| title | Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region |
| title_full | Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region |
| title_fullStr | Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region |
| title_full_unstemmed | Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region |
| title_short | Clinical and epidemiological features of hemorrhagic fever with renal syndrome course in Perm region |
| title_sort | clinical and epidemiological features of hemorrhagic fever with renal syndrome course in perm region |
| topic | геморрагическая лихорадка с почечным синдромом заболеваемость особенности клинического течения пермский край |
| url | https://journal.niidi.ru/jofin/article/view/44 |
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