A machine learning-based SNP-set analysis approach for identifying disease-associated susceptibility loci
Abstract Identifying disease-associated susceptibility loci is one of the most pressing and crucial challenges in modeling complex diseases. Existing approaches to biomarker discovery are subject to several limitations including underpowered detection, neglect for variant interactions, and restricti...
Main Authors: | Princess P. Silva, Joverlyn D. Gaudillo, Julianne A. Vilela, Ranzivelle Marianne L. Roxas-Villanueva, Beatrice J. Tiangco, Mario R. Domingo, Jason R. Albia |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2022-09-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-022-19708-1 |
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