Ultrasonographical Evaluation of the Median Nerve Mobility in Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis
Diagnostic ultrasound is widely used for evaluating carpal tunnel syndrome (CTS), an entrapment neuropathy of the median nerve (MN). Decreased mobility of the MN inside the carpal tunnel has been reported in CTS, and various methods have been used to evaluate MN mobility; however, there is still no...
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| Format: | Article |
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MDPI AG
2022-09-01
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| Series: | Diagnostics |
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| Online Access: | https://www.mdpi.com/2075-4418/12/10/2349 |
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| author | Yu-Ting Huang Chii-Jen Chen You-Wei Wang Po-Lin Peng Yan-Ting Luo Yi-Shiung Horng |
| author_facet | Yu-Ting Huang Chii-Jen Chen You-Wei Wang Po-Lin Peng Yan-Ting Luo Yi-Shiung Horng |
| author_sort | Yu-Ting Huang |
| collection | DOAJ |
| description | Diagnostic ultrasound is widely used for evaluating carpal tunnel syndrome (CTS), an entrapment neuropathy of the median nerve (MN). Decreased mobility of the MN inside the carpal tunnel has been reported in CTS, and various methods have been used to evaluate MN mobility; however, there is still no conclusive understanding of its connection with CTS. The purpose of this study is to conduct a systematic review and meta-analysis of the current published literature on ultrasonographic evaluations of transverse and longitudinal MN displacement and to identify the relationship between MN mobility and CTS. This study was conducted in accordance with the 2020 PRISMA statement and the Cochrane Collaboration Handbook. Comparative studies that investigated differences in MN displacement between CTS patients and healthy controls were retrieved by searching the Cochrane Library, Embase and PubMed. A total of 15 case–control studies were included. Nine of 12 studies evaluating transverse MN displacement and 4 of 5 studies evaluating longitudinal MN gliding showed that the MN was less mobile in CTS patients than in healthy subjects. Despite the large heterogeneity among the 15 included studies, this systematic review and meta-analysis provide evidence that the mobility of the MN is significantly reduced in both transverse and longitudinal planes in CTS patients compared to healthy controls. Five of the 15 included studies reported that a decrease in transverse or longitudinal MN displacement in CTS was correlated with clinical symptoms or with severity as measured by a nerve conduction study (NCS). |
| first_indexed | 2024-03-09T20:22:27Z |
| format | Article |
| id | doaj.art-8a261eb563b5453ba0e2e2dabcf4210c |
| institution | Directory Open Access Journal |
| issn | 2075-4418 |
| language | English |
| last_indexed | 2024-03-09T20:22:27Z |
| publishDate | 2022-09-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Diagnostics |
| spelling | doaj.art-8a261eb563b5453ba0e2e2dabcf4210c2023-11-23T23:43:45ZengMDPI AGDiagnostics2075-44182022-09-011210234910.3390/diagnostics12102349Ultrasonographical Evaluation of the Median Nerve Mobility in Carpal Tunnel Syndrome: A Systematic Review and Meta-AnalysisYu-Ting Huang0Chii-Jen Chen1You-Wei Wang2Po-Lin Peng3Yan-Ting Luo4Yi-Shiung Horng5Department of Medical Education, Taipei Tzuchi Hospital, Buddhist Tzuchi Medical Foundation, New Taipei City 23142, TaiwanDepartment of Computer Science and Information Engineering, Tamkang University, New Taipei City 25137, TaiwanDepartment of Computer Science and Information Engineering, National Taiwan University, Taipei 10617, TaiwanDepartment of Medical Education, Taipei Tzuchi Hospital, Buddhist Tzuchi Medical Foundation, New Taipei City 23142, TaiwanDepartment of Physical Medicine and Rehabilitation, Taipei Tzuchi Hospital, Buddhist Tzuchi Medical Foundation, No. 289, Jianguo Rd., Xindian Dist., New Taipei City 23142, TaiwanDepartment of Physical Medicine and Rehabilitation, Taipei Tzuchi Hospital, Buddhist Tzuchi Medical Foundation, No. 289, Jianguo Rd., Xindian Dist., New Taipei City 23142, TaiwanDiagnostic ultrasound is widely used for evaluating carpal tunnel syndrome (CTS), an entrapment neuropathy of the median nerve (MN). Decreased mobility of the MN inside the carpal tunnel has been reported in CTS, and various methods have been used to evaluate MN mobility; however, there is still no conclusive understanding of its connection with CTS. The purpose of this study is to conduct a systematic review and meta-analysis of the current published literature on ultrasonographic evaluations of transverse and longitudinal MN displacement and to identify the relationship between MN mobility and CTS. This study was conducted in accordance with the 2020 PRISMA statement and the Cochrane Collaboration Handbook. Comparative studies that investigated differences in MN displacement between CTS patients and healthy controls were retrieved by searching the Cochrane Library, Embase and PubMed. A total of 15 case–control studies were included. Nine of 12 studies evaluating transverse MN displacement and 4 of 5 studies evaluating longitudinal MN gliding showed that the MN was less mobile in CTS patients than in healthy subjects. Despite the large heterogeneity among the 15 included studies, this systematic review and meta-analysis provide evidence that the mobility of the MN is significantly reduced in both transverse and longitudinal planes in CTS patients compared to healthy controls. Five of the 15 included studies reported that a decrease in transverse or longitudinal MN displacement in CTS was correlated with clinical symptoms or with severity as measured by a nerve conduction study (NCS).https://www.mdpi.com/2075-4418/12/10/2349carpal tunnel syndromemedian nervenerve displacementultrasound imagessystematic reviewmeta-analysis |
| spellingShingle | Yu-Ting Huang Chii-Jen Chen You-Wei Wang Po-Lin Peng Yan-Ting Luo Yi-Shiung Horng Ultrasonographical Evaluation of the Median Nerve Mobility in Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis Diagnostics carpal tunnel syndrome median nerve nerve displacement ultrasound images systematic review meta-analysis |
| title | Ultrasonographical Evaluation of the Median Nerve Mobility in Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis |
| title_full | Ultrasonographical Evaluation of the Median Nerve Mobility in Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis |
| title_fullStr | Ultrasonographical Evaluation of the Median Nerve Mobility in Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis |
| title_full_unstemmed | Ultrasonographical Evaluation of the Median Nerve Mobility in Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis |
| title_short | Ultrasonographical Evaluation of the Median Nerve Mobility in Carpal Tunnel Syndrome: A Systematic Review and Meta-Analysis |
| title_sort | ultrasonographical evaluation of the median nerve mobility in carpal tunnel syndrome a systematic review and meta analysis |
| topic | carpal tunnel syndrome median nerve nerve displacement ultrasound images systematic review meta-analysis |
| url | https://www.mdpi.com/2075-4418/12/10/2349 |
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