Review of Konjac Glucomannan Structure, Properties, Gelation Mechanism, and Application in Medical Biology
Konjac glucomannan (KGM) is a naturally occurring macromolecular polysaccharide that exhibits remarkable film–forming and gel–forming properties, and a high degree of biocompatibility and biodegradability. The helical structure of KGM is maintained by the acetyl group, which plays a crucial role in...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-04-01
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| Series: | Polymers |
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| Online Access: | https://www.mdpi.com/2073-4360/15/8/1852 |
| _version_ | 1797603745427619840 |
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| author | Yilan Sun Xiaowei Xu Qinhua Zhang Di Zhang Xiaoyu Xie Hanlin Zhou Zhenzhen Wu Renyi Liu Jie Pang |
| author_facet | Yilan Sun Xiaowei Xu Qinhua Zhang Di Zhang Xiaoyu Xie Hanlin Zhou Zhenzhen Wu Renyi Liu Jie Pang |
| author_sort | Yilan Sun |
| collection | DOAJ |
| description | Konjac glucomannan (KGM) is a naturally occurring macromolecular polysaccharide that exhibits remarkable film–forming and gel–forming properties, and a high degree of biocompatibility and biodegradability. The helical structure of KGM is maintained by the acetyl group, which plays a crucial role in preserving its structural integrity. Various degradation methods, including the topological structure, can enhance the stability of KGM and improve its biological activity. Recent research has focused on modifying KGM to enhance its properties, utilizing multi–scale simulation, mechanical experiments, and biosensor research. This review presents a comprehensive overview of the structure and properties of KGM, recent advancements in non–alkali thermally irreversible gel research, and its applications in biomedical materials and related areas of research. Additionally, this review outlines prospects for future KGM research, providing valuable research ideas for follow–up experiments. |
| first_indexed | 2024-03-11T04:36:17Z |
| format | Article |
| id | doaj.art-8a27063cf21f44ed87d4e221e27dda1a |
| institution | Directory Open Access Journal |
| issn | 2073-4360 |
| language | English |
| last_indexed | 2024-03-11T04:36:17Z |
| publishDate | 2023-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Polymers |
| spelling | doaj.art-8a27063cf21f44ed87d4e221e27dda1a2023-11-17T21:01:29ZengMDPI AGPolymers2073-43602023-04-01158185210.3390/polym15081852Review of Konjac Glucomannan Structure, Properties, Gelation Mechanism, and Application in Medical BiologyYilan Sun0Xiaowei Xu1Qinhua Zhang2Di Zhang3Xiaoyu Xie4Hanlin Zhou5Zhenzhen Wu6Renyi Liu7Jie Pang8Center for Agroforestry Mega Data Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaCollege of Food Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaCollege of Food Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaCollege of Food Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaCollege of Food Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaCollege of Food Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaCollege of Food Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaCenter for Agroforestry Mega Data Science, Haixia Institute of Science and Technology, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaCollege of Food Sciences, Fujian Agriculture and Forestry University, Fuzhou 350002, ChinaKonjac glucomannan (KGM) is a naturally occurring macromolecular polysaccharide that exhibits remarkable film–forming and gel–forming properties, and a high degree of biocompatibility and biodegradability. The helical structure of KGM is maintained by the acetyl group, which plays a crucial role in preserving its structural integrity. Various degradation methods, including the topological structure, can enhance the stability of KGM and improve its biological activity. Recent research has focused on modifying KGM to enhance its properties, utilizing multi–scale simulation, mechanical experiments, and biosensor research. This review presents a comprehensive overview of the structure and properties of KGM, recent advancements in non–alkali thermally irreversible gel research, and its applications in biomedical materials and related areas of research. Additionally, this review outlines prospects for future KGM research, providing valuable research ideas for follow–up experiments.https://www.mdpi.com/2073-4360/15/8/1852konjac glucomannanstructurepropertygelationmedical biology |
| spellingShingle | Yilan Sun Xiaowei Xu Qinhua Zhang Di Zhang Xiaoyu Xie Hanlin Zhou Zhenzhen Wu Renyi Liu Jie Pang Review of Konjac Glucomannan Structure, Properties, Gelation Mechanism, and Application in Medical Biology Polymers konjac glucomannan structure property gelation medical biology |
| title | Review of Konjac Glucomannan Structure, Properties, Gelation Mechanism, and Application in Medical Biology |
| title_full | Review of Konjac Glucomannan Structure, Properties, Gelation Mechanism, and Application in Medical Biology |
| title_fullStr | Review of Konjac Glucomannan Structure, Properties, Gelation Mechanism, and Application in Medical Biology |
| title_full_unstemmed | Review of Konjac Glucomannan Structure, Properties, Gelation Mechanism, and Application in Medical Biology |
| title_short | Review of Konjac Glucomannan Structure, Properties, Gelation Mechanism, and Application in Medical Biology |
| title_sort | review of konjac glucomannan structure properties gelation mechanism and application in medical biology |
| topic | konjac glucomannan structure property gelation medical biology |
| url | https://www.mdpi.com/2073-4360/15/8/1852 |
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