Arterial relaxation is coupled to inhibition of mitochondrial fission in arterial smooth muscle cells: comparison of vasorelaxant effects of verapamil and phentolamine

Arterial relaxation is coupled to inhibition of mitochondrial fission in arterial smooth muscle cells: comparison of vasorelaxant effects of verapamil and phentolamine

Mitochondria are morphologically dynamic organelles which undergo fission and fusion processes. Our previous study found that arterial constriction was always accompanied by increased mitochondrial fission in smooth muscle cells, whereas inhibition of mitochondrial fission in smooth muscle cells was...

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Bibliographic Details
Main Authors: Jing Jin, Xin Shen, Yu Tai, Shanliang Li, Mingyu Liu, Changlin Zhen, Xiuchen Xuan, Xiyue Zhang, Nan Hu, Xinzi Zhang, Deli Dong
Format: Article
Language:English
Published: Elsevier 2017-05-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Artery
Mitochondrial fission
Phentolamine
Vasorelaxation
Verapamil
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383516303550

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