Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold Nanorods
Herein we exploit the molecular engineering capability to immobilize monolayer of polyamidoamine dendrimer on gold electrode, which exhibit enhanced charge transfer and biocompatibility. Polyamidoamine (PAMAM generation 5.0) dendrimers were used as template/stabilizers for gold nanoparticle growth,...
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Tsinghua University Press
2010-09-01
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| Series: | Nano Biomedicine and Engineering |
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| Online Access: | https://www.sciopen.com/article/10.5101/nbe.v2i3.p182-188 |
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| author | Xueqing Zhang Bifeng Pan Kan Wang Jing Ruan Chenchen Bao Hao Yang Rong He Daxiang Cui |
| author_facet | Xueqing Zhang Bifeng Pan Kan Wang Jing Ruan Chenchen Bao Hao Yang Rong He Daxiang Cui |
| author_sort | Xueqing Zhang |
| collection | DOAJ |
| description | Herein we exploit the molecular engineering capability to immobilize monolayer of polyamidoamine dendrimer on gold electrode, which exhibit enhanced charge transfer and biocompatibility. Polyamidoamine (PAMAM generation 5.0) dendrimers were used as template/stabilizers for gold nanoparticle growth, with Au@PAMAM nanoparticles serving as surface modifier to produce monolayer film. TEM, UV-vis spectroscopy, and AFM were used to characterize the formation of monolayer Au@PAMAM on gold surface. The cyclic voltammetry (CV) and Impedance measurements of Au@PAMAM modified gold electrodes demonstrate electrochemistry properties of modified electrode. Furthermore, Au@PAMAM coating can greatly increased the biocompatibility of gold electrode as determined by cell growth curves |
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| id | doaj.art-8a2aa448ce3c4e80b8beea53f11d6f80 |
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| issn | 2150-5578 |
| language | English |
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| publishDate | 2010-09-01 |
| publisher | Tsinghua University Press |
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| series | Nano Biomedicine and Engineering |
| spelling | doaj.art-8a2aa448ce3c4e80b8beea53f11d6f802024-10-03T08:09:07ZengTsinghua University PressNano Biomedicine and Engineering2150-55782010-09-012318218810.5101/nbe.v2i3.p182-188Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold NanorodsXueqing Zhang0Bifeng Pan1Kan Wang2Jing Ruan3Chenchen Bao4Hao Yang5Rong He6Daxiang Cui7Department of Bio-Nano-Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, ChinaDepartment of Bio-Nano-Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, ChinaDepartment of Bio-Nano-Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, ChinaDepartment of Bio-Nano-Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, ChinaDepartment of Bio-Nano-Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, ChinaDepartment of Bio-Nano-Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, ChinaDepartment of Bio-Nano-Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, ChinaDepartment of Bio-Nano-Science and Engineering, National Key Laboratory of Nano/Micro Fabrication Technology, Key Laboratory for Thin Film and Microfabrication of Ministry of Education, Institute of Micro-Nano Science and Technology, Shanghai Jiao Tong University, Shanghai 200240, ChinaHerein we exploit the molecular engineering capability to immobilize monolayer of polyamidoamine dendrimer on gold electrode, which exhibit enhanced charge transfer and biocompatibility. Polyamidoamine (PAMAM generation 5.0) dendrimers were used as template/stabilizers for gold nanoparticle growth, with Au@PAMAM nanoparticles serving as surface modifier to produce monolayer film. TEM, UV-vis spectroscopy, and AFM were used to characterize the formation of monolayer Au@PAMAM on gold surface. The cyclic voltammetry (CV) and Impedance measurements of Au@PAMAM modified gold electrodes demonstrate electrochemistry properties of modified electrode. Furthermore, Au@PAMAM coating can greatly increased the biocompatibility of gold electrode as determined by cell growth curveshttps://www.sciopen.com/article/10.5101/nbe.v2i3.p182-188monolayergold electrodecyclic voltammetrybiocompatibility |
| spellingShingle | Xueqing Zhang Bifeng Pan Kan Wang Jing Ruan Chenchen Bao Hao Yang Rong He Daxiang Cui Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold Nanorods Nano Biomedicine and Engineering monolayer gold electrode cyclic voltammetry biocompatibility |
| title | Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold Nanorods |
| title_full | Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold Nanorods |
| title_fullStr | Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold Nanorods |
| title_full_unstemmed | Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold Nanorods |
| title_short | Electrochemical Property and Cell Toxicity of Gold Electrode Modified by Monolayer PAMAM Encapsulated Gold Nanorods |
| title_sort | electrochemical property and cell toxicity of gold electrode modified by monolayer pamam encapsulated gold nanorods |
| topic | monolayer gold electrode cyclic voltammetry biocompatibility |
| url | https://www.sciopen.com/article/10.5101/nbe.v2i3.p182-188 |
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