Churg–Strauss syndrome associated with antiphospholipid antibodies in a patient with recurrent myocardial and cerebral ischemia
Marino Paroli,1 Alessandro Polidoro,1 Simone Romano,1 Daniele Accapezzato21Department of Biotechnology and Medical-Surgical Sciences, 2Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, ItalyAbstract: We report on a case of Churg–Strauss syndrom...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2012-11-01
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| Series: | International Medical Case Reports Journal |
| Online Access: | http://www.dovepress.com/churgndashstrauss-syndrome-associated-with-antiphospholipid-antibodies-a11413 |
| _version_ | 1811196917806268416 |
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| author | Paroli M Polidoro A Romano S Accapezzato D |
| author_facet | Paroli M Polidoro A Romano S Accapezzato D |
| author_sort | Paroli M |
| collection | DOAJ |
| description | Marino Paroli,1 Alessandro Polidoro,1 Simone Romano,1 Daniele Accapezzato21Department of Biotechnology and Medical-Surgical Sciences, 2Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, ItalyAbstract: We report on a case of Churg–Strauss syndrome (CSS) associated with the presence of antiphospholipid antibodies. The patient had a history of recurrent myocardial infarction and presented with acute ischemic cerebral disease. Eosinophilia with typical lung and skin lesions led us to diagnose the patient with CCS. We hypothesize that the presence of antiphospholipid antibodies significantly contributed to the ischemic events. We suggest that the search for antiphospholipid antibodies should be included in the laboratory work-up in CSS patients and patients affected by primary systemic vasculitides in general. Moreover, anticoagulant treatment appears to be warranted in all CSS patients and antiphospholipid antibodies to counteract this thrombosis-favoring association.Keywords: Churg–Strauss syndrome, antiphospholipid antibodies, ischemic disease |
| first_indexed | 2024-04-12T01:06:42Z |
| format | Article |
| id | doaj.art-8a2bb05e735f4e1f890c69d0190d2367 |
| institution | Directory Open Access Journal |
| issn | 1179-142X |
| language | English |
| last_indexed | 2024-04-12T01:06:42Z |
| publishDate | 2012-11-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Medical Case Reports Journal |
| spelling | doaj.art-8a2bb05e735f4e1f890c69d0190d23672022-12-22T03:54:14ZengDove Medical PressInternational Medical Case Reports Journal1179-142X2012-11-012012default7981Churg–Strauss syndrome associated with antiphospholipid antibodies in a patient with recurrent myocardial and cerebral ischemiaParoli MPolidoro ARomano SAccapezzato DMarino Paroli,1 Alessandro Polidoro,1 Simone Romano,1 Daniele Accapezzato21Department of Biotechnology and Medical-Surgical Sciences, 2Department of Internal Medicine and Medical Specialties, Sapienza University of Rome, Rome, ItalyAbstract: We report on a case of Churg–Strauss syndrome (CSS) associated with the presence of antiphospholipid antibodies. The patient had a history of recurrent myocardial infarction and presented with acute ischemic cerebral disease. Eosinophilia with typical lung and skin lesions led us to diagnose the patient with CCS. We hypothesize that the presence of antiphospholipid antibodies significantly contributed to the ischemic events. We suggest that the search for antiphospholipid antibodies should be included in the laboratory work-up in CSS patients and patients affected by primary systemic vasculitides in general. Moreover, anticoagulant treatment appears to be warranted in all CSS patients and antiphospholipid antibodies to counteract this thrombosis-favoring association.Keywords: Churg–Strauss syndrome, antiphospholipid antibodies, ischemic diseasehttp://www.dovepress.com/churgndashstrauss-syndrome-associated-with-antiphospholipid-antibodies-a11413 |
| spellingShingle | Paroli M Polidoro A Romano S Accapezzato D Churg–Strauss syndrome associated with antiphospholipid antibodies in a patient with recurrent myocardial and cerebral ischemia International Medical Case Reports Journal |
| title | Churg–Strauss syndrome associated with antiphospholipid antibodies in a patient with recurrent myocardial and cerebral ischemia |
| title_full | Churg–Strauss syndrome associated with antiphospholipid antibodies in a patient with recurrent myocardial and cerebral ischemia |
| title_fullStr | Churg–Strauss syndrome associated with antiphospholipid antibodies in a patient with recurrent myocardial and cerebral ischemia |
| title_full_unstemmed | Churg–Strauss syndrome associated with antiphospholipid antibodies in a patient with recurrent myocardial and cerebral ischemia |
| title_short | Churg–Strauss syndrome associated with antiphospholipid antibodies in a patient with recurrent myocardial and cerebral ischemia |
| title_sort | churg amp ndash strauss syndrome associated with antiphospholipid antibodies in a patient with recurrent myocardial and cerebral ischemia |
| url | http://www.dovepress.com/churgndashstrauss-syndrome-associated-with-antiphospholipid-antibodies-a11413 |
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