Anthrax Postexposure Prophylaxis in Postal Workers, Connecticut, 2001

After inhalational anthrax was diagnosed in a Connecticut woman on November 20, 2001, postexposure prophylaxis was recommended for postal workers at the regional mail facility serving the patient’s area. Although environmental testing at the facility yielded negative results, subsequent testing conf...

Full description

Bibliographic Details
Main Authors: Jennifer L. Williams, Stephanie S. Noviello, Kevin S. Griffith, Heather Wurtzel, Jennifer Hamborsky, Joseph F. Perz, Ian T. Williams, James L. Hadler, David L. Swerdlow, Renee Ridzon
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2002-10-01
Series:Emerging Infectious Diseases
Subjects:
Online Access:https://wwwnc.cdc.gov/eid/article/8/10/02-0346_article
_version_ 1819237100241813504
author Jennifer L. Williams
Stephanie S. Noviello
Kevin S. Griffith
Heather Wurtzel
Jennifer Hamborsky
Joseph F. Perz
Ian T. Williams
James L. Hadler
David L. Swerdlow
Renee Ridzon
author_facet Jennifer L. Williams
Stephanie S. Noviello
Kevin S. Griffith
Heather Wurtzel
Jennifer Hamborsky
Joseph F. Perz
Ian T. Williams
James L. Hadler
David L. Swerdlow
Renee Ridzon
author_sort Jennifer L. Williams
collection DOAJ
description After inhalational anthrax was diagnosed in a Connecticut woman on November 20, 2001, postexposure prophylaxis was recommended for postal workers at the regional mail facility serving the patient’s area. Although environmental testing at the facility yielded negative results, subsequent testing confirmed the presence of Bacillus anthracis. We distributed questionnaires to 100 randomly selected postal workers within 20 days of initial prophylaxis. Ninety-four workers obtained antibiotics, 68 of whom started postexposure prophylaxis and 21 discontinued. Postal workers who stopped or never started taking prophylaxis cited as reasons disbelief regarding anthrax exposure, problems with adverse events, and initial reports of negative cultures. Postal workers with adverse events reported predominant symptoms of gastrointestinal distress and headache. The influence of these concerns on adherence suggests that communication about risks of acquiring anthrax, education about adverse events, and careful management of adverse events are essential elements in increasing adherence.
first_indexed 2024-12-23T13:14:57Z
format Article
id doaj.art-8a2bed7741b8493bb1b3bde4a3b9943c
institution Directory Open Access Journal
issn 1080-6040
1080-6059
language English
last_indexed 2024-12-23T13:14:57Z
publishDate 2002-10-01
publisher Centers for Disease Control and Prevention
record_format Article
series Emerging Infectious Diseases
spelling doaj.art-8a2bed7741b8493bb1b3bde4a3b9943c2022-12-21T17:45:37ZengCenters for Disease Control and PreventionEmerging Infectious Diseases1080-60401080-60592002-10-018101133113710.3201/eid0810.020346Anthrax Postexposure Prophylaxis in Postal Workers, Connecticut, 2001Jennifer L. WilliamsStephanie S. NovielloKevin S. GriffithHeather WurtzelJennifer HamborskyJoseph F. PerzIan T. WilliamsJames L. HadlerDavid L. SwerdlowRenee RidzonAfter inhalational anthrax was diagnosed in a Connecticut woman on November 20, 2001, postexposure prophylaxis was recommended for postal workers at the regional mail facility serving the patient’s area. Although environmental testing at the facility yielded negative results, subsequent testing confirmed the presence of Bacillus anthracis. We distributed questionnaires to 100 randomly selected postal workers within 20 days of initial prophylaxis. Ninety-four workers obtained antibiotics, 68 of whom started postexposure prophylaxis and 21 discontinued. Postal workers who stopped or never started taking prophylaxis cited as reasons disbelief regarding anthrax exposure, problems with adverse events, and initial reports of negative cultures. Postal workers with adverse events reported predominant symptoms of gastrointestinal distress and headache. The influence of these concerns on adherence suggests that communication about risks of acquiring anthrax, education about adverse events, and careful management of adverse events are essential elements in increasing adherence.https://wwwnc.cdc.gov/eid/article/8/10/02-0346_articleadverse effectsAnthraxBacillus anthracisciprofloxacinConnecticutdoxycycline
spellingShingle Jennifer L. Williams
Stephanie S. Noviello
Kevin S. Griffith
Heather Wurtzel
Jennifer Hamborsky
Joseph F. Perz
Ian T. Williams
James L. Hadler
David L. Swerdlow
Renee Ridzon
Anthrax Postexposure Prophylaxis in Postal Workers, Connecticut, 2001
Emerging Infectious Diseases
adverse effects
Anthrax
Bacillus anthracis
ciprofloxacin
Connecticut
doxycycline
title Anthrax Postexposure Prophylaxis in Postal Workers, Connecticut, 2001
title_full Anthrax Postexposure Prophylaxis in Postal Workers, Connecticut, 2001
title_fullStr Anthrax Postexposure Prophylaxis in Postal Workers, Connecticut, 2001
title_full_unstemmed Anthrax Postexposure Prophylaxis in Postal Workers, Connecticut, 2001
title_short Anthrax Postexposure Prophylaxis in Postal Workers, Connecticut, 2001
title_sort anthrax postexposure prophylaxis in postal workers connecticut 2001
topic adverse effects
Anthrax
Bacillus anthracis
ciprofloxacin
Connecticut
doxycycline
url https://wwwnc.cdc.gov/eid/article/8/10/02-0346_article
work_keys_str_mv AT jenniferlwilliams anthraxpostexposureprophylaxisinpostalworkersconnecticut2001
AT stephaniesnoviello anthraxpostexposureprophylaxisinpostalworkersconnecticut2001
AT kevinsgriffith anthraxpostexposureprophylaxisinpostalworkersconnecticut2001
AT heatherwurtzel anthraxpostexposureprophylaxisinpostalworkersconnecticut2001
AT jenniferhamborsky anthraxpostexposureprophylaxisinpostalworkersconnecticut2001
AT josephfperz anthraxpostexposureprophylaxisinpostalworkersconnecticut2001
AT iantwilliams anthraxpostexposureprophylaxisinpostalworkersconnecticut2001
AT jameslhadler anthraxpostexposureprophylaxisinpostalworkersconnecticut2001
AT davidlswerdlow anthraxpostexposureprophylaxisinpostalworkersconnecticut2001
AT reneeridzon anthraxpostexposureprophylaxisinpostalworkersconnecticut2001