Overview and recent trends of systematic reviews and meta-analyses in hepatology

A systematic review (SR) is a research methodology that involves a comprehensive search for and analysis of relevant studies on a specific topic. A strict and objective research process is conducted that comprises a systematic and comprehensive literature search in accordance with predetermined incl...

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Main Authors: Gaeun Kim, Soon Koo Baik
Format: Article
Language:English
Published: Korean Association for the Study of the Liver 2014-06-01
Series:Clinical and Molecular Hepatology
Subjects:
Online Access:http://e-cmh.org/upload/pdf/cmh-20-137.pdf
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author Gaeun Kim
Soon Koo Baik
author_facet Gaeun Kim
Soon Koo Baik
author_sort Gaeun Kim
collection DOAJ
description A systematic review (SR) is a research methodology that involves a comprehensive search for and analysis of relevant studies on a specific topic. A strict and objective research process is conducted that comprises a systematic and comprehensive literature search in accordance with predetermined inclusion/exclusion criteria, and an assessment of the risk of bias of the selected literature. SRs require a multidisciplinary approach that necessitates cooperation with clinical experts, methodologists, other experts, and statisticians. A meta-analysis (MA) is a statistical method of quantitatively synthesizing data, where possible, from the primary literature selected for the SR. Review articles differ from SRs in that they lack a systematic methodology such as a literature search, selection of studies according to strict criteria, assessment of risk bias, and synthesis of the study results. The importance of evidence-based medicine (EBM) in the decision-making for public policy has recently been increasing thanks to the realization that it should be based on scientific research data. SRs and MAs are essential for EBM strategy and evidence-based clinical practice guidelines. This review addresses the current trends in SRs and MAs in the field of hepatology via a search of recently published articles in the Cochrane Library and Ovid-MEDLINE.
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spelling doaj.art-8a2cab8a50ab432b90f6545f562993a72022-12-21T19:42:07ZengKorean Association for the Study of the LiverClinical and Molecular Hepatology2287-27282287-285X2014-06-0120213715010.3350/cmh.2014.20.2.1371070Overview and recent trends of systematic reviews and meta-analyses in hepatologyGaeun Kim0Soon Koo Baik1Department of Nursing, Keimyung University College of Nursing, Daegu, Korea.Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea.A systematic review (SR) is a research methodology that involves a comprehensive search for and analysis of relevant studies on a specific topic. A strict and objective research process is conducted that comprises a systematic and comprehensive literature search in accordance with predetermined inclusion/exclusion criteria, and an assessment of the risk of bias of the selected literature. SRs require a multidisciplinary approach that necessitates cooperation with clinical experts, methodologists, other experts, and statisticians. A meta-analysis (MA) is a statistical method of quantitatively synthesizing data, where possible, from the primary literature selected for the SR. Review articles differ from SRs in that they lack a systematic methodology such as a literature search, selection of studies according to strict criteria, assessment of risk bias, and synthesis of the study results. The importance of evidence-based medicine (EBM) in the decision-making for public policy has recently been increasing thanks to the realization that it should be based on scientific research data. SRs and MAs are essential for EBM strategy and evidence-based clinical practice guidelines. This review addresses the current trends in SRs and MAs in the field of hepatology via a search of recently published articles in the Cochrane Library and Ovid-MEDLINE.http://e-cmh.org/upload/pdf/cmh-20-137.pdfMeta-analysisSystematic reviewHepatology
spellingShingle Gaeun Kim
Soon Koo Baik
Overview and recent trends of systematic reviews and meta-analyses in hepatology
Clinical and Molecular Hepatology
Meta-analysis
Systematic review
Hepatology
title Overview and recent trends of systematic reviews and meta-analyses in hepatology
title_full Overview and recent trends of systematic reviews and meta-analyses in hepatology
title_fullStr Overview and recent trends of systematic reviews and meta-analyses in hepatology
title_full_unstemmed Overview and recent trends of systematic reviews and meta-analyses in hepatology
title_short Overview and recent trends of systematic reviews and meta-analyses in hepatology
title_sort overview and recent trends of systematic reviews and meta analyses in hepatology
topic Meta-analysis
Systematic review
Hepatology
url http://e-cmh.org/upload/pdf/cmh-20-137.pdf
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