Development, Characterization and Pharmacological Evaluation of Cannabidiol-Loaded Long Circulating Niosomes

Development, Characterization and Pharmacological Evaluation of Cannabidiol-Loaded Long Circulating Niosomes

Cannabidiol (CBD) is a promising drug candidate with pleiotropic pharmacological activity, whose low aqueous solubility and unfavorable pharmacokinetics have presented obstacles to its full clinical implementation. The rational design of nanocarriers, including niosomes for CBD encapsulation, can pr...

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Bibliographic Details
Main Authors: Viliana Gugleva, Katerina Ahchiyska, Dilyana Georgieva, Rositsa Mihaylova, Spiro Konstantinov, Erik Dimitrov, Natalia Toncheva-Moncheva, Stanislav Rangelov, Aleksander Forys, Barbara Trzebicka, Denitsa Momekova
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Pharmaceutics
Subjects:
star-shaped polyglycidol- poly(ε-caprolactone) copolymers
copolymer-modified niosomes
steric stabilization
EPR effect
cannabidiol
apoptosis
Online Access:https://www.mdpi.com/1999-4923/15/10/2414

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https://www.mdpi.com/1999-4923/15/10/2414

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