Human Cardiac Progenitor Cell-Derived Extracellular Vesicles Exhibit Promising Potential for Supporting Cardiac Repair in Vitro

Human Cardiac Progenitor Cell-Derived Extracellular Vesicles Exhibit Promising Potential for Supporting Cardiac Repair in Vitro

Although human Cardiac Progenitor Cells (hCPCs) are not retained by host myocardium they still improve cardiac function when injected into ischemic heart. Emerging evidence supports the hypothesis that hCPC beneficial effects are induced by paracrine action on resident cells. Extracellular vesicles...

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Bibliographic Details
Main Authors: Veronica Romano, Immacolata Belviso, Anna Maria Sacco, Domenico Cozzolino, Daria Nurzynska, Cristiano Amarelli, Ciro Maiello, Felice Sirico, Franca Di Meglio, Clotilde Castaldo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Physiology
Subjects:
extracellular vesicles
human cardiac progenitor cells
human cardiac fibroblasts
cardiac regenerative medicine
paracrine effects
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.879046/full

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