Diverse Localization and Protein Binding Abilities of Glyceraldehyde-3-Phosphate Dehydrogenase in Pathogenic Bacteria: The Key to its Multifunctionality?

Diverse Localization and Protein Binding Abilities of Glyceraldehyde-3-Phosphate Dehydrogenase in Pathogenic Bacteria: The Key to its Multifunctionality?

Bacterial proteins exhibiting two or more unrelated functions, referred to as moonlighting proteins, are suggested to contribute to full virulence manifestation in pathogens. An expanding number of published studies have revealed the glycolytic enzyme glyceraldehyde-3-phosphate dehydrogenase (GAPDH)...

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Bibliographic Details
Main Authors: Monika Kopeckova, Ivona Pavkova, Jiri Stulik
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
glyceraldehyde-3-phosphate dehydrogenase
pathogenic bacteria
protein-protein interaction (PPI)
moonlighting proteins
localization
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2020.00089/full

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