Extracellular Vesicles, New Players in Sepsis and Acute Respiratory Distress Syndrome
Sepsis refers to a complex syndrome associated with physiological, pathological, and biochemical abnormalities resulted from infection. Sepsis is the major cause of acute respiratory distress syndrome (ARDS). Extracellular vesicles (EVs) are serving as new messengers to mediate cell-cell communicati...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-04-01
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| Series: | Frontiers in Cellular and Infection Microbiology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fcimb.2022.853840/full |
| _version_ | 1819047430392381440 |
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| author | Wenqiang Jing Huijuan Wang Liying Zhan Wei Yan |
| author_facet | Wenqiang Jing Huijuan Wang Liying Zhan Wei Yan |
| author_sort | Wenqiang Jing |
| collection | DOAJ |
| description | Sepsis refers to a complex syndrome associated with physiological, pathological, and biochemical abnormalities resulted from infection. Sepsis is the major cause of acute respiratory distress syndrome (ARDS). Extracellular vesicles (EVs) are serving as new messengers to mediate cell-cell communication in vivo. Non-coding RNAs, proteins and metabolites encapsulated by EVs could result in either pro-inflammatory or anti-inflammatory effects in the recipient cells. Pathogens or host cells derived EVs play an important role in pathogens infection during the occurrence and development of sepsis and ARDS. Additionally, we summarize the potential application for EVs in diagnosis, prevention and treatment for sepsis and ARDS. |
| first_indexed | 2024-12-21T11:00:14Z |
| format | Article |
| id | doaj.art-8a427f3cc3b74d64947bf0d15c9152bd |
| institution | Directory Open Access Journal |
| issn | 2235-2988 |
| language | English |
| last_indexed | 2024-12-21T11:00:14Z |
| publishDate | 2022-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cellular and Infection Microbiology |
| spelling | doaj.art-8a427f3cc3b74d64947bf0d15c9152bd2022-12-21T19:06:22ZengFrontiers Media S.A.Frontiers in Cellular and Infection Microbiology2235-29882022-04-011210.3389/fcimb.2022.853840853840Extracellular Vesicles, New Players in Sepsis and Acute Respiratory Distress SyndromeWenqiang Jing0Huijuan Wang1Liying Zhan2Wei Yan3Department of Critical Care Medicine, Renmin Hospital of Wuhan University, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, ChinaDepartment of Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, ChinaDepartment of Critical Care Medicine, Renmin Hospital of Wuhan University, Wuhan, ChinaDepartment of Critical Care Medicine, Renmin Hospital of Wuhan University, Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, ChinaSepsis refers to a complex syndrome associated with physiological, pathological, and biochemical abnormalities resulted from infection. Sepsis is the major cause of acute respiratory distress syndrome (ARDS). Extracellular vesicles (EVs) are serving as new messengers to mediate cell-cell communication in vivo. Non-coding RNAs, proteins and metabolites encapsulated by EVs could result in either pro-inflammatory or anti-inflammatory effects in the recipient cells. Pathogens or host cells derived EVs play an important role in pathogens infection during the occurrence and development of sepsis and ARDS. Additionally, we summarize the potential application for EVs in diagnosis, prevention and treatment for sepsis and ARDS.https://www.frontiersin.org/articles/10.3389/fcimb.2022.853840/fullsepsisARDSextracellular vesiclesdiagnosisengineering |
| spellingShingle | Wenqiang Jing Huijuan Wang Liying Zhan Wei Yan Extracellular Vesicles, New Players in Sepsis and Acute Respiratory Distress Syndrome Frontiers in Cellular and Infection Microbiology sepsis ARDS extracellular vesicles diagnosis engineering |
| title | Extracellular Vesicles, New Players in Sepsis and Acute Respiratory Distress Syndrome |
| title_full | Extracellular Vesicles, New Players in Sepsis and Acute Respiratory Distress Syndrome |
| title_fullStr | Extracellular Vesicles, New Players in Sepsis and Acute Respiratory Distress Syndrome |
| title_full_unstemmed | Extracellular Vesicles, New Players in Sepsis and Acute Respiratory Distress Syndrome |
| title_short | Extracellular Vesicles, New Players in Sepsis and Acute Respiratory Distress Syndrome |
| title_sort | extracellular vesicles new players in sepsis and acute respiratory distress syndrome |
| topic | sepsis ARDS extracellular vesicles diagnosis engineering |
| url | https://www.frontiersin.org/articles/10.3389/fcimb.2022.853840/full |
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