A mucin like gene different from the previously reported members of the mucin like gene families is transcribed in Trypanosoma cruzi but not in Trypanosoma rangeli
Trypanosoma cruzi expresses mucin like glycoproteins encoded by a complex multigene family. In this work, we report the transcription in T. cruzi but not in T. rangeli of a mucin type gene automatically annotated by the T. cruzi genome project. The gene showed no nucleotide similarities with the pre...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Fundação Oswaldo Cruz (FIOCRUZ)
2005-07-01
|
| Series: | Memorias do Instituto Oswaldo Cruz |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000400009 |
| _version_ | 1827842530369077248 |
|---|---|
| author | Teresa Abate Mónica Rincón Zoraida Díaz-Bello Lilian Spencer Alexis Rodríguez-Acosta |
| author_facet | Teresa Abate Mónica Rincón Zoraida Díaz-Bello Lilian Spencer Alexis Rodríguez-Acosta |
| author_sort | Teresa Abate |
| collection | DOAJ |
| description | Trypanosoma cruzi expresses mucin like glycoproteins encoded by a complex multigene family. In this work, we report the transcription in T. cruzi but not in T. rangeli of a mucin type gene automatically annotated by the T. cruzi genome project. The gene showed no nucleotide similarities with the previously reported T. cruzi mucin like genes, although the computational analysis of the deduced protein showed that it has the characteristic features of mucins: a signal peptide sequence, O-glycosylation sites, and glycosylphosphatidylinositol (GPI) anchor sequence. The presence in this gene of N- terminal and C- terminal coding sequences common to other annotated mucin like genes suggests the existence of a new mucin like gene family. |
| first_indexed | 2024-03-12T08:10:53Z |
| format | Article |
| id | doaj.art-8a432ab867bb47198903b431e0d500d7 |
| institution | Directory Open Access Journal |
| issn | 0074-0276 1678-8060 |
| language | English |
| last_indexed | 2024-03-12T08:10:53Z |
| publishDate | 2005-07-01 |
| publisher | Fundação Oswaldo Cruz (FIOCRUZ) |
| record_format | Article |
| series | Memorias do Instituto Oswaldo Cruz |
| spelling | doaj.art-8a432ab867bb47198903b431e0d500d72023-09-02T19:07:09ZengFundação Oswaldo Cruz (FIOCRUZ)Memorias do Instituto Oswaldo Cruz0074-02761678-80602005-07-01100439139510.1590/S0074-02762005000400009A mucin like gene different from the previously reported members of the mucin like gene families is transcribed in Trypanosoma cruzi but not in Trypanosoma rangeliTeresa AbateMónica RincónZoraida Díaz-BelloLilian SpencerAlexis Rodríguez-AcostaTrypanosoma cruzi expresses mucin like glycoproteins encoded by a complex multigene family. In this work, we report the transcription in T. cruzi but not in T. rangeli of a mucin type gene automatically annotated by the T. cruzi genome project. The gene showed no nucleotide similarities with the previously reported T. cruzi mucin like genes, although the computational analysis of the deduced protein showed that it has the characteristic features of mucins: a signal peptide sequence, O-glycosylation sites, and glycosylphosphatidylinositol (GPI) anchor sequence. The presence in this gene of N- terminal and C- terminal coding sequences common to other annotated mucin like genes suggests the existence of a new mucin like gene family.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000400009mucin like geneTrypanosoma cruziTrypanosoma rangeli |
| spellingShingle | Teresa Abate Mónica Rincón Zoraida Díaz-Bello Lilian Spencer Alexis Rodríguez-Acosta A mucin like gene different from the previously reported members of the mucin like gene families is transcribed in Trypanosoma cruzi but not in Trypanosoma rangeli Memorias do Instituto Oswaldo Cruz mucin like gene Trypanosoma cruzi Trypanosoma rangeli |
| title | A mucin like gene different from the previously reported members of the mucin like gene families is transcribed in Trypanosoma cruzi but not in Trypanosoma rangeli |
| title_full | A mucin like gene different from the previously reported members of the mucin like gene families is transcribed in Trypanosoma cruzi but not in Trypanosoma rangeli |
| title_fullStr | A mucin like gene different from the previously reported members of the mucin like gene families is transcribed in Trypanosoma cruzi but not in Trypanosoma rangeli |
| title_full_unstemmed | A mucin like gene different from the previously reported members of the mucin like gene families is transcribed in Trypanosoma cruzi but not in Trypanosoma rangeli |
| title_short | A mucin like gene different from the previously reported members of the mucin like gene families is transcribed in Trypanosoma cruzi but not in Trypanosoma rangeli |
| title_sort | mucin like gene different from the previously reported members of the mucin like gene families is transcribed in trypanosoma cruzi but not in trypanosoma rangeli |
| topic | mucin like gene Trypanosoma cruzi Trypanosoma rangeli |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762005000400009 |
| work_keys_str_mv | AT teresaabate amucinlikegenedifferentfromthepreviouslyreportedmembersofthemucinlikegenefamiliesistranscribedintrypanosomacruzibutnotintrypanosomarangeli AT monicarincon amucinlikegenedifferentfromthepreviouslyreportedmembersofthemucinlikegenefamiliesistranscribedintrypanosomacruzibutnotintrypanosomarangeli AT zoraidadiazbello amucinlikegenedifferentfromthepreviouslyreportedmembersofthemucinlikegenefamiliesistranscribedintrypanosomacruzibutnotintrypanosomarangeli AT lilianspencer amucinlikegenedifferentfromthepreviouslyreportedmembersofthemucinlikegenefamiliesistranscribedintrypanosomacruzibutnotintrypanosomarangeli AT alexisrodriguezacosta amucinlikegenedifferentfromthepreviouslyreportedmembersofthemucinlikegenefamiliesistranscribedintrypanosomacruzibutnotintrypanosomarangeli AT teresaabate mucinlikegenedifferentfromthepreviouslyreportedmembersofthemucinlikegenefamiliesistranscribedintrypanosomacruzibutnotintrypanosomarangeli AT monicarincon mucinlikegenedifferentfromthepreviouslyreportedmembersofthemucinlikegenefamiliesistranscribedintrypanosomacruzibutnotintrypanosomarangeli AT zoraidadiazbello mucinlikegenedifferentfromthepreviouslyreportedmembersofthemucinlikegenefamiliesistranscribedintrypanosomacruzibutnotintrypanosomarangeli AT lilianspencer mucinlikegenedifferentfromthepreviouslyreportedmembersofthemucinlikegenefamiliesistranscribedintrypanosomacruzibutnotintrypanosomarangeli AT alexisrodriguezacosta mucinlikegenedifferentfromthepreviouslyreportedmembersofthemucinlikegenefamiliesistranscribedintrypanosomacruzibutnotintrypanosomarangeli |