The Paracrine Role of Endothelial Cells in Bone Formation via CXCR4/SDF-1 Pathway

The Paracrine Role of Endothelial Cells in Bone Formation via CXCR4/SDF-1 Pathway

Vascularization is a prerequisite for bone formation. Endothelial progenitor cells (EPCs) stimulate bone formation by creating a vascular network. Moreover, EPCs secrete various bioactive molecules that may regulate bone formation. The aim of this research was to shed light on the pathways of EPCs i...

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Bibliographic Details
Main Authors: Tal Tamari, Rawan Kawar-Jaraisy, Ofri Doppelt, Ben Giladi, Nadin Sabbah, Hadar Zigdon-Giladi
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
endothelial cells
mesenchymal stem cells
bone
angiogenesis
paracrine
SDF-1
Online Access:https://www.mdpi.com/2073-4409/9/6/1325

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