Oral antimicrobial peptides: Types and role in the oral cavity
Antimicrobial peptides (AMPs) are a wide-ranging class of host-defense molecules that act early to contest against microbial invasion and challenge. These are small cationic peptides that play an important in the development of innate immunity. In the oral cavity, the AMPs are produced by the saliva...
Main Authors: | , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2016-09-01
|
Series: | Saudi Pharmaceutical Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1319016415000535 |
_version_ | 1818292410623459328 |
---|---|
author | Zohaib Khurshid Mustafa Naseem Zeeshan Sheikh Shariq Najeeb Sana Shahab Muhammad Sohail Zafar |
author_facet | Zohaib Khurshid Mustafa Naseem Zeeshan Sheikh Shariq Najeeb Sana Shahab Muhammad Sohail Zafar |
author_sort | Zohaib Khurshid |
collection | DOAJ |
description | Antimicrobial peptides (AMPs) are a wide-ranging class of host-defense molecules that act early to contest against microbial invasion and challenge. These are small cationic peptides that play an important in the development of innate immunity. In the oral cavity, the AMPs are produced by the salivary glands and the oral epithelium and serve defensive purposes. The aim of this review was to discuss the types and functions of oral AMPs and their role in combating microorganisms and infections in the oral cavity. |
first_indexed | 2024-12-13T02:59:31Z |
format | Article |
id | doaj.art-8a469997f3e34e959ace320f04f1e9bd |
institution | Directory Open Access Journal |
issn | 1319-0164 |
language | English |
last_indexed | 2024-12-13T02:59:31Z |
publishDate | 2016-09-01 |
publisher | Elsevier |
record_format | Article |
series | Saudi Pharmaceutical Journal |
spelling | doaj.art-8a469997f3e34e959ace320f04f1e9bd2022-12-22T00:01:52ZengElsevierSaudi Pharmaceutical Journal1319-01642016-09-0124551552410.1016/j.jsps.2015.02.015Oral antimicrobial peptides: Types and role in the oral cavityZohaib Khurshid0Mustafa Naseem1Zeeshan Sheikh2Shariq Najeeb3Sana Shahab4Muhammad Sohail Zafar5School of Materials and Metallurgy, University of Birmingham, United KingdomDepartment of Community Dentistry and Preventive Dentistry, School of Dentistry, Ziauddin University, PakistanFaculty of Dentistry, University of Toronto, Toronto, CanadaSchool of Dentistry, Al-Farabi Dental College, Saudi ArabiaDepartment of Dental Materials Science, Sir Syed College of Medical Sciences for Girls, PakistanDepartment of Restorative Dentistry, College of Dentistry, Taibah University, Madinah Al-Munawwarah, Saudi ArabiaAntimicrobial peptides (AMPs) are a wide-ranging class of host-defense molecules that act early to contest against microbial invasion and challenge. These are small cationic peptides that play an important in the development of innate immunity. In the oral cavity, the AMPs are produced by the salivary glands and the oral epithelium and serve defensive purposes. The aim of this review was to discuss the types and functions of oral AMPs and their role in combating microorganisms and infections in the oral cavity.http://www.sciencedirect.com/science/article/pii/S1319016415000535Antimicrobial peptides (AMPs)Oral cavityDefensinsCathelicidinsHistatinsDental applications |
spellingShingle | Zohaib Khurshid Mustafa Naseem Zeeshan Sheikh Shariq Najeeb Sana Shahab Muhammad Sohail Zafar Oral antimicrobial peptides: Types and role in the oral cavity Saudi Pharmaceutical Journal Antimicrobial peptides (AMPs) Oral cavity Defensins Cathelicidins Histatins Dental applications |
title | Oral antimicrobial peptides: Types and role in the oral cavity |
title_full | Oral antimicrobial peptides: Types and role in the oral cavity |
title_fullStr | Oral antimicrobial peptides: Types and role in the oral cavity |
title_full_unstemmed | Oral antimicrobial peptides: Types and role in the oral cavity |
title_short | Oral antimicrobial peptides: Types and role in the oral cavity |
title_sort | oral antimicrobial peptides types and role in the oral cavity |
topic | Antimicrobial peptides (AMPs) Oral cavity Defensins Cathelicidins Histatins Dental applications |
url | http://www.sciencedirect.com/science/article/pii/S1319016415000535 |
work_keys_str_mv | AT zohaibkhurshid oralantimicrobialpeptidestypesandroleintheoralcavity AT mustafanaseem oralantimicrobialpeptidestypesandroleintheoralcavity AT zeeshansheikh oralantimicrobialpeptidestypesandroleintheoralcavity AT shariqnajeeb oralantimicrobialpeptidestypesandroleintheoralcavity AT sanashahab oralantimicrobialpeptidestypesandroleintheoralcavity AT muhammadsohailzafar oralantimicrobialpeptidestypesandroleintheoralcavity |