Oral antimicrobial peptides: Types and role in the oral cavity

Antimicrobial peptides (AMPs) are a wide-ranging class of host-defense molecules that act early to contest against microbial invasion and challenge. These are small cationic peptides that play an important in the development of innate immunity. In the oral cavity, the AMPs are produced by the saliva...

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Main Authors: Zohaib Khurshid, Mustafa Naseem, Zeeshan Sheikh, Shariq Najeeb, Sana Shahab, Muhammad Sohail Zafar
Format: Article
Language:English
Published: Elsevier 2016-09-01
Series:Saudi Pharmaceutical Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1319016415000535
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author Zohaib Khurshid
Mustafa Naseem
Zeeshan Sheikh
Shariq Najeeb
Sana Shahab
Muhammad Sohail Zafar
author_facet Zohaib Khurshid
Mustafa Naseem
Zeeshan Sheikh
Shariq Najeeb
Sana Shahab
Muhammad Sohail Zafar
author_sort Zohaib Khurshid
collection DOAJ
description Antimicrobial peptides (AMPs) are a wide-ranging class of host-defense molecules that act early to contest against microbial invasion and challenge. These are small cationic peptides that play an important in the development of innate immunity. In the oral cavity, the AMPs are produced by the salivary glands and the oral epithelium and serve defensive purposes. The aim of this review was to discuss the types and functions of oral AMPs and their role in combating microorganisms and infections in the oral cavity.
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spelling doaj.art-8a469997f3e34e959ace320f04f1e9bd2022-12-22T00:01:52ZengElsevierSaudi Pharmaceutical Journal1319-01642016-09-0124551552410.1016/j.jsps.2015.02.015Oral antimicrobial peptides: Types and role in the oral cavityZohaib Khurshid0Mustafa Naseem1Zeeshan Sheikh2Shariq Najeeb3Sana Shahab4Muhammad Sohail Zafar5School of Materials and Metallurgy, University of Birmingham, United KingdomDepartment of Community Dentistry and Preventive Dentistry, School of Dentistry, Ziauddin University, PakistanFaculty of Dentistry, University of Toronto, Toronto, CanadaSchool of Dentistry, Al-Farabi Dental College, Saudi ArabiaDepartment of Dental Materials Science, Sir Syed College of Medical Sciences for Girls, PakistanDepartment of Restorative Dentistry, College of Dentistry, Taibah University, Madinah Al-Munawwarah, Saudi ArabiaAntimicrobial peptides (AMPs) are a wide-ranging class of host-defense molecules that act early to contest against microbial invasion and challenge. These are small cationic peptides that play an important in the development of innate immunity. In the oral cavity, the AMPs are produced by the salivary glands and the oral epithelium and serve defensive purposes. The aim of this review was to discuss the types and functions of oral AMPs and their role in combating microorganisms and infections in the oral cavity.http://www.sciencedirect.com/science/article/pii/S1319016415000535Antimicrobial peptides (AMPs)Oral cavityDefensinsCathelicidinsHistatinsDental applications
spellingShingle Zohaib Khurshid
Mustafa Naseem
Zeeshan Sheikh
Shariq Najeeb
Sana Shahab
Muhammad Sohail Zafar
Oral antimicrobial peptides: Types and role in the oral cavity
Saudi Pharmaceutical Journal
Antimicrobial peptides (AMPs)
Oral cavity
Defensins
Cathelicidins
Histatins
Dental applications
title Oral antimicrobial peptides: Types and role in the oral cavity
title_full Oral antimicrobial peptides: Types and role in the oral cavity
title_fullStr Oral antimicrobial peptides: Types and role in the oral cavity
title_full_unstemmed Oral antimicrobial peptides: Types and role in the oral cavity
title_short Oral antimicrobial peptides: Types and role in the oral cavity
title_sort oral antimicrobial peptides types and role in the oral cavity
topic Antimicrobial peptides (AMPs)
Oral cavity
Defensins
Cathelicidins
Histatins
Dental applications
url http://www.sciencedirect.com/science/article/pii/S1319016415000535
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AT sanashahab oralantimicrobialpeptidestypesandroleintheoralcavity
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