Factors influencing pharmaceutical pricing - a scoping review of academic literature in health science

Introduction Pharmaceutical pricing has only recently gained space in mainstream health science literature. Objectives Bibliometric and content description of health science academic literature and ad hoc analysis of grey literature on factors influencing pharmaceutical pricing on databases commonly...

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Main Authors: Maria Angelica Borges dos Santos, Leticia Lucia dos Santos Dias, Cláudia Du Bocage Santos Pinto, Rondineli Mendes da Silva, Claudia Garcia Serpa Osorio-de-Castro
Format: Article
Language:English
Published: Taylor & Francis Group 2019-12-01
Series:Journal of Pharmaceutical Policy and Practice
Subjects:
Online Access:http://dx.doi.org/10.1186/s40545-019-0183-0
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author Maria Angelica Borges dos Santos
Leticia Lucia dos Santos Dias
Cláudia Du Bocage Santos Pinto
Rondineli Mendes da Silva
Claudia Garcia Serpa Osorio-de-Castro
author_facet Maria Angelica Borges dos Santos
Leticia Lucia dos Santos Dias
Cláudia Du Bocage Santos Pinto
Rondineli Mendes da Silva
Claudia Garcia Serpa Osorio-de-Castro
author_sort Maria Angelica Borges dos Santos
collection DOAJ
description Introduction Pharmaceutical pricing has only recently gained space in mainstream health science literature. Objectives Bibliometric and content description of health science academic literature and ad hoc analysis of grey literature on factors influencing pharmaceutical pricing on databases commonly accessed by healthcare professionals. Methods Scoping study with no time limits performed in Medline, Scopus and Scielo, and relevant sites and databases for grey literature, using search terms with database-appropriate keywords. Results Two hundred four articles were published in 103 peer-reviewed journals between 1981 and 2016 (last search year). In grey literature 78 documents were retrieved in the final selection. Five key thematic clusters for analysing pharmaceutical pricing emerged: market dynamics, segmented into (i) supply-related, (ii) consumer-related and (iii) product-related; (iv) trading strategies, either buyer’s or seller’s and (v) regulatory approach. In peer-reviewed literature there is an overall dominance of themes referring to trading strategies and regulatory approaches and a wide thematic cluster scope. Over half of this literature was produced after the year 2010. International agency technical papers make up the most significant contributions of grey literature, with a clear focus on regulatory approaches to pricing and wider consideration of emerging countries. Research lags in the literature on factors affecting pharmaceutical pricing include impacts of financing schemes, market liberalization, internet trading and biosimilars on prices, with insufficient discussion identified for the effects of discounts/rebates, profits and price transparency. Conclusions Interest in pharmaceutical pricing literature is increasing. Robust evidence-producing study designs for pricing interventions will be a welcome development.
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spelling doaj.art-8a49cbf4fd3c43109289d545077f4d122023-12-07T15:28:02ZengTaylor & Francis GroupJournal of Pharmaceutical Policy and Practice2052-32112019-12-0112110.1186/s40545-019-0183-012315113Factors influencing pharmaceutical pricing - a scoping review of academic literature in health scienceMaria Angelica Borges dos Santos0Leticia Lucia dos Santos Dias1Cláudia Du Bocage Santos Pinto2Rondineli Mendes da Silva3Claudia Garcia Serpa Osorio-de-Castro4Vice Direção de Escola de Governo, Escola Nacional de Saúde Pública Sérgio Arouca, Fundação Oswaldo Cruz,Fundação Oswaldo Cruz,Instituto Integrado de Saúde da Universidade Federal de Mato Grosso do Sul (INISA/UFMS),Departamento de Política de Medicamentos e Assistência Farmacêutica da Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz,Departamento de Política de Medicamentos e Assistência Farmacêutica da Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz,Introduction Pharmaceutical pricing has only recently gained space in mainstream health science literature. Objectives Bibliometric and content description of health science academic literature and ad hoc analysis of grey literature on factors influencing pharmaceutical pricing on databases commonly accessed by healthcare professionals. Methods Scoping study with no time limits performed in Medline, Scopus and Scielo, and relevant sites and databases for grey literature, using search terms with database-appropriate keywords. Results Two hundred four articles were published in 103 peer-reviewed journals between 1981 and 2016 (last search year). In grey literature 78 documents were retrieved in the final selection. Five key thematic clusters for analysing pharmaceutical pricing emerged: market dynamics, segmented into (i) supply-related, (ii) consumer-related and (iii) product-related; (iv) trading strategies, either buyer’s or seller’s and (v) regulatory approach. In peer-reviewed literature there is an overall dominance of themes referring to trading strategies and regulatory approaches and a wide thematic cluster scope. Over half of this literature was produced after the year 2010. International agency technical papers make up the most significant contributions of grey literature, with a clear focus on regulatory approaches to pricing and wider consideration of emerging countries. Research lags in the literature on factors affecting pharmaceutical pricing include impacts of financing schemes, market liberalization, internet trading and biosimilars on prices, with insufficient discussion identified for the effects of discounts/rebates, profits and price transparency. Conclusions Interest in pharmaceutical pricing literature is increasing. Robust evidence-producing study designs for pricing interventions will be a welcome development.http://dx.doi.org/10.1186/s40545-019-0183-0medicine pricegovernment regulationreview literature as topic
spellingShingle Maria Angelica Borges dos Santos
Leticia Lucia dos Santos Dias
Cláudia Du Bocage Santos Pinto
Rondineli Mendes da Silva
Claudia Garcia Serpa Osorio-de-Castro
Factors influencing pharmaceutical pricing - a scoping review of academic literature in health science
Journal of Pharmaceutical Policy and Practice
medicine price
government regulation
review literature as topic
title Factors influencing pharmaceutical pricing - a scoping review of academic literature in health science
title_full Factors influencing pharmaceutical pricing - a scoping review of academic literature in health science
title_fullStr Factors influencing pharmaceutical pricing - a scoping review of academic literature in health science
title_full_unstemmed Factors influencing pharmaceutical pricing - a scoping review of academic literature in health science
title_short Factors influencing pharmaceutical pricing - a scoping review of academic literature in health science
title_sort factors influencing pharmaceutical pricing a scoping review of academic literature in health science
topic medicine price
government regulation
review literature as topic
url http://dx.doi.org/10.1186/s40545-019-0183-0
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