ATR protects centromere identity by promoting DAXX association with PML nuclear bodies

ATR protects centromere identity by promoting DAXX association with PML nuclear bodies

Summary: Centromere protein A (CENP-A) defines centromere identity and nucleates kinetochore formation for mitotic chromosome segregation. Here, we show that ataxia telangiectasia and Rad3-related (ATR) kinase, a master regulator of the DNA damage response, protects CENP-A occupancy at interphase ce...

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Bibliographic Details
Main Authors: Isabelle Trier, Elizabeth M. Black, Yoon Ki Joo, Lilian Kabeche
Format: Article
Language:English
Published: Elsevier 2023-05-01
Series:Cell Reports
Subjects:
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723005065

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