Ultrasound-Guided Injections of HYADD4 for Knee Osteoarthritis Improves Pain and Functional Outcomes at 3, 6, and 12 Months without Changes in Measured Synovial Fluid, Serum Collagen Biomarkers, or Most Synovial Fluid Biomarker Proteins at 3 Months

Ultrasound-Guided Injections of HYADD4 for Knee Osteoarthritis Improves Pain and Functional Outcomes at 3, 6, and 12 Months without Changes in Measured Synovial Fluid, Serum Collagen Biomarkers, or Most Synovial Fluid Biomarker Proteins at 3 Months

Background: Prior studies have demonstrated improved efficacy when intra-articular (IA) therapeutics are injected using ultrasound (US) guidance. The aim of this study was to determine if clinical improvement in pain and function after IA hyaluronic acid injections using US is associated with change...

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Bibliographic Details
Main Authors: Richard T. Meehan, Mary T. Gill, Eric D. Hoffman, Claire M. Coeshott, Manuel D. Galvan, Molly L. Wolf, Isabelle A. Amigues, Liudmila M. Kastsianok, Elizabeth A. Regan, James L. Crooks, Gregory J. Czuczman, Vijaya Knight
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Journal of Clinical Medicine
Subjects:
osteoarthritis
ultrasound
synovial fluid
biomarkers
cytokines
Online Access:https://www.mdpi.com/2077-0383/12/17/5541

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