Correlation of blood, salivary glucose levels and bloo HbA1c% in healthy and previously diagnosed Diabetes Mellitus Type 2 in a sec ion of patients of Baghdad hospital, Iraq
Background: Diabetes mellitus is a metabolic disorder affecting people worldwide, which require constant monitoring of their glucose levels. Commonly employed procedures include collection of blood or urine samples causing discomfort to the patients. Necessity arises to find alternative non invasiv...
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| Format: | Article |
| Language: | English |
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University of Baghdad/ Al-Kindy College of Medicine
2016-06-01
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| Series: | مجله كليه طب الكندي |
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| Online Access: | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/335 |
| _version_ | 1798002230791503872 |
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| author | Jamela A K Jouda , Iyden Kamil Mohammed* Samal H K Al-Jaff** |
| author_facet | Jamela A K Jouda , Iyden Kamil Mohammed* Samal H K Al-Jaff** |
| author_sort | Jamela A K Jouda |
| collection | DOAJ |
| description |
Background: Diabetes mellitus is a metabolic disorder affecting people worldwide, which require constant monitoring of their glucose levels. Commonly employed procedures include collection of blood or urine samples causing discomfort to the patients. Necessity arises to find alternative non invasive technique is required to monitor glucose levels. Saliva is one of most abundant secretions in the human body and its collection is easy, noninvasive and painless technique. Objective: The aim of this study was to determine the efficacy of saliva as a diagnostic tool by study the correlation between blood and salivary glucose levels and glycosylated hemoglobin (HbA1c%) in diabetes and non diabetes, and the comparison of salivary glucose level and blood HbA1c% with serum glucose level in healthy and diabetic subjects. Type of study: cross- sectional study.Method: Saliva and blood samples were collected from 40 patients visited the Baghdad hospital in Iraq who were previously diagnosed with non-insulin-dependent (type 2) diabetes mellitus and 10 healthy as control (male and female) in age group of 30-65 years. The samples were examined to determine blood and salivary glucose level by the glucose oxidase- peroxidase method and blood HbA1c% by the ion exchange resin method. Results: Our results showed significantly higher salivary and serum glucose level in diabetes compared to control and significantly positive correlation between salivary and serum glucose in diabetes, control, and both groups together; the blood HbA1c% in diabetes was significantly higher compared to control and found a positive correlation between blood HbA1c% and salivary and serum glucose level in diabetes and control. Conclusion: salivary glucose appears to be an indicator of serum glucose concentration in diabetes.
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| first_indexed | 2024-04-11T11:48:47Z |
| format | Article |
| id | doaj.art-8a59812c48494d8f84f97fc0943e7acb |
| institution | Directory Open Access Journal |
| issn | 1810-9543 2521-4365 |
| language | English |
| last_indexed | 2024-04-11T11:48:47Z |
| publishDate | 2016-06-01 |
| publisher | University of Baghdad/ Al-Kindy College of Medicine |
| record_format | Article |
| series | مجله كليه طب الكندي |
| spelling | doaj.art-8a59812c48494d8f84f97fc0943e7acb2022-12-22T04:25:27ZengUniversity of Baghdad/ Al-Kindy College of Medicineمجله كليه طب الكندي1810-95432521-43652016-06-01121Correlation of blood, salivary glucose levels and bloo HbA1c% in healthy and previously diagnosed Diabetes Mellitus Type 2 in a sec ion of patients of Baghdad hospital, IraqJamela A K Jouda0, Iyden Kamil Mohammed*1Samal H K Al-Jaff**2Department of Biology / College of Science / AlMustansiriyiah University / IraqDepartment of Biomedical/ College of Al-Khawarzmy Engineering/Baghdad university/ Iraqge of Science / AlMustansiriyiah University Background: Diabetes mellitus is a metabolic disorder affecting people worldwide, which require constant monitoring of their glucose levels. Commonly employed procedures include collection of blood or urine samples causing discomfort to the patients. Necessity arises to find alternative non invasive technique is required to monitor glucose levels. Saliva is one of most abundant secretions in the human body and its collection is easy, noninvasive and painless technique. Objective: The aim of this study was to determine the efficacy of saliva as a diagnostic tool by study the correlation between blood and salivary glucose levels and glycosylated hemoglobin (HbA1c%) in diabetes and non diabetes, and the comparison of salivary glucose level and blood HbA1c% with serum glucose level in healthy and diabetic subjects. Type of study: cross- sectional study.Method: Saliva and blood samples were collected from 40 patients visited the Baghdad hospital in Iraq who were previously diagnosed with non-insulin-dependent (type 2) diabetes mellitus and 10 healthy as control (male and female) in age group of 30-65 years. The samples were examined to determine blood and salivary glucose level by the glucose oxidase- peroxidase method and blood HbA1c% by the ion exchange resin method. Results: Our results showed significantly higher salivary and serum glucose level in diabetes compared to control and significantly positive correlation between salivary and serum glucose in diabetes, control, and both groups together; the blood HbA1c% in diabetes was significantly higher compared to control and found a positive correlation between blood HbA1c% and salivary and serum glucose level in diabetes and control. Conclusion: salivary glucose appears to be an indicator of serum glucose concentration in diabetes. https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/335Glucose levelHbA1c%Diabetes diseasesaliva |
| spellingShingle | Jamela A K Jouda , Iyden Kamil Mohammed* Samal H K Al-Jaff** Correlation of blood, salivary glucose levels and bloo HbA1c% in healthy and previously diagnosed Diabetes Mellitus Type 2 in a sec ion of patients of Baghdad hospital, Iraq مجله كليه طب الكندي Glucose level HbA1c% Diabetes disease saliva |
| title | Correlation of blood, salivary glucose levels and bloo HbA1c% in healthy and previously diagnosed Diabetes Mellitus Type 2 in a sec ion of patients of Baghdad hospital, Iraq |
| title_full | Correlation of blood, salivary glucose levels and bloo HbA1c% in healthy and previously diagnosed Diabetes Mellitus Type 2 in a sec ion of patients of Baghdad hospital, Iraq |
| title_fullStr | Correlation of blood, salivary glucose levels and bloo HbA1c% in healthy and previously diagnosed Diabetes Mellitus Type 2 in a sec ion of patients of Baghdad hospital, Iraq |
| title_full_unstemmed | Correlation of blood, salivary glucose levels and bloo HbA1c% in healthy and previously diagnosed Diabetes Mellitus Type 2 in a sec ion of patients of Baghdad hospital, Iraq |
| title_short | Correlation of blood, salivary glucose levels and bloo HbA1c% in healthy and previously diagnosed Diabetes Mellitus Type 2 in a sec ion of patients of Baghdad hospital, Iraq |
| title_sort | correlation of blood salivary glucose levels and bloo hba1c in healthy and previously diagnosed diabetes mellitus type 2 in a sec ion of patients of baghdad hospital iraq |
| topic | Glucose level HbA1c% Diabetes disease saliva |
| url | https://jkmc.uobaghdad.edu.iq/index.php/MEDICAL/article/view/335 |
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