Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy
Objective: This study analyzed the correlation between the average segment width (ASW) and gamma passing rate according to the multi-leaf collimator (MLC) position error. Method: To evaluate the changes in the gamma passing rate according to the MLC position error, 21 volumetric modulated arc therap...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2021-11-01
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| Series: | Technology in Cancer Research & Treatment |
| Online Access: | https://doi.org/10.1177/15330338211059937 |
| _version_ | 1818692232019968000 |
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| author | Young Min Moon PhD Sang Il Bae PhD Moo Jae Han PhD Wan Jeon MD Tosol Yu MD Chul Won Choi MD, PhD Jin Young Kim PhD |
| author_facet | Young Min Moon PhD Sang Il Bae PhD Moo Jae Han PhD Wan Jeon MD Tosol Yu MD Chul Won Choi MD, PhD Jin Young Kim PhD |
| author_sort | Young Min Moon PhD |
| collection | DOAJ |
| description | Objective: This study analyzed the correlation between the average segment width (ASW) and gamma passing rate according to the multi-leaf collimator (MLC) position error. Method: To evaluate the changes in the gamma passing rate according to the MLC position error, 21 volumetric modulated arc therapy (VMAT) plans were generated using pelvic lymph node metastatic prostate cancer patient's data which is sensitive to MLC position errors as they involve several long, narrow, irregular fields. The ASW for each VMAT plan was calculated using our own code developed using Visual Basic for Applications (VBA). The gamma passing rate of the VMAT plan according to the MLC position error was evaluated using ArcCHECK (Sun Nuclear, Melbourne, FL, USA) while inducing symmetric MLC position errors in 0.25 mm intervals from −1 mm to +1 mm in the infinity medical linear accelerator (Elekta AB, Stockholm, Sweden). Finally, we examined the correlation between the change in the passing rate ( γ gradient ) due to the MLC position error and the ASW in VMAT through linear regression analysis using the least squares method. Results: The ASW and γ gradient were found to have a linear correlation according to the MLC position error, and the coefficient of determination was 0.88. For a 1 mm position error of MLC in VMAT, the gamma passing rate improved by approximately 11.9% as the ASW increased by 10 mm. Conclusion: These results are expected to be employed as guidelines to minimize the dose uncertainty due to MLC position error in VMAT. |
| first_indexed | 2024-12-17T12:54:31Z |
| format | Article |
| id | doaj.art-8a59da70025e454796d2a2fc22467351 |
| institution | Directory Open Access Journal |
| issn | 1533-0338 |
| language | English |
| last_indexed | 2024-12-17T12:54:31Z |
| publishDate | 2021-11-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Technology in Cancer Research & Treatment |
| spelling | doaj.art-8a59da70025e454796d2a2fc224673512022-12-21T21:47:31ZengSAGE PublishingTechnology in Cancer Research & Treatment1533-03382021-11-012010.1177/15330338211059937Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc TherapyYoung Min Moon PhD0Sang Il Bae PhD1Moo Jae Han PhD2Wan Jeon MD3Tosol Yu MD4Chul Won Choi MD, PhD5Jin Young Kim PhD6 , Gijang-gun, Busan, Republic of Korea , Gijang-gun, Busan, Republic of Korea Collage of Medicine, , Busan, Republic of Korea , Gijang-gun, Busan, Republic of Korea , Gijang-gun, Busan, Republic of Korea , Gijang-gun, Busan, Republic of Korea , Gijang-gun, Busan, Republic of KoreaObjective: This study analyzed the correlation between the average segment width (ASW) and gamma passing rate according to the multi-leaf collimator (MLC) position error. Method: To evaluate the changes in the gamma passing rate according to the MLC position error, 21 volumetric modulated arc therapy (VMAT) plans were generated using pelvic lymph node metastatic prostate cancer patient's data which is sensitive to MLC position errors as they involve several long, narrow, irregular fields. The ASW for each VMAT plan was calculated using our own code developed using Visual Basic for Applications (VBA). The gamma passing rate of the VMAT plan according to the MLC position error was evaluated using ArcCHECK (Sun Nuclear, Melbourne, FL, USA) while inducing symmetric MLC position errors in 0.25 mm intervals from −1 mm to +1 mm in the infinity medical linear accelerator (Elekta AB, Stockholm, Sweden). Finally, we examined the correlation between the change in the passing rate ( γ gradient ) due to the MLC position error and the ASW in VMAT through linear regression analysis using the least squares method. Results: The ASW and γ gradient were found to have a linear correlation according to the MLC position error, and the coefficient of determination was 0.88. For a 1 mm position error of MLC in VMAT, the gamma passing rate improved by approximately 11.9% as the ASW increased by 10 mm. Conclusion: These results are expected to be employed as guidelines to minimize the dose uncertainty due to MLC position error in VMAT.https://doi.org/10.1177/15330338211059937 |
| spellingShingle | Young Min Moon PhD Sang Il Bae PhD Moo Jae Han PhD Wan Jeon MD Tosol Yu MD Chul Won Choi MD, PhD Jin Young Kim PhD Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy Technology in Cancer Research & Treatment |
| title | Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy |
| title_full | Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy |
| title_fullStr | Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy |
| title_full_unstemmed | Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy |
| title_short | Correlation Between Average Segment Width and Gamma Passing Rate as a Function of MLC Position Error in Volumetric Modulated Arc Therapy |
| title_sort | correlation between average segment width and gamma passing rate as a function of mlc position error in volumetric modulated arc therapy |
| url | https://doi.org/10.1177/15330338211059937 |
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