BAR-encapsulated nanoparticles for the inhibition and disruption of Porphyromonas gingivalis–Streptococcus gordonii biofilms

BAR-encapsulated nanoparticles for the inhibition and disruption of Porphyromonas gingivalis–Streptococcus gordonii biofilms

Abstract Background Porphyromonas gingivalis adherence to oral streptococci is a key point in the pathogenesis of periodontal diseases (Honda in Cell Host Microbe 10:423–425, 2011). Previous work in our groups has shown that a region of the streptococcal antigen denoted BAR (SspB Adherence Region) i...

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Bibliographic Details
Main Authors: Mohamed Y. Mahmoud, Donald R. Demuth, Jill M. Steinbach-Rankins
Format: Article
Language:English
Published: BMC 2018-09-01
Series:Journal of Nanobiotechnology
Subjects:
Polymer nanoparticle
Poly(lactic-co-glycolic acid)
Peptide delivery
Drug delivery
Porphyromonas gingivalis
Streptococcus gordonii
Online Access:http://link.springer.com/article/10.1186/s12951-018-0396-4

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