Chimeric infectious bursal disease virus-like particles as potent vaccines for eradication of established HPV-16 E7-dependent tumors.

Chimeric infectious bursal disease virus-like particles as potent vaccines for eradication of established HPV-16 E7-dependent tumors.

Cervical cancer is caused by persistent high-risk human papillomavirus (HR-HPV) infection and represents the second most frequent gynecological malignancy in the world. The HPV-16 type accounts for up to 55% of all cervical cancers. The HPV-16 oncoproteins E6 and E7 are necessary for induction and m...

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Main Authors: Juan Martin Caballero, Ana Garzón, Leticia González-Cintado, Wioleta Kowalczyk, Ignacio Jimenez Torres, Gloria Calderita, Margarita Rodriguez, Virgínia Gondar, Juan Jose Bernal, Carlos Ardavín, David Andreu, Thomas Zürcher, Cayetano von Kobbe
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3534127?pdf=render

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