Parafoveal exudative vascular anomalous complex and its characteristics of multi-modal imaging in 11 cases
AIM: To observe the imaging characteristics of multi-modal imaging in perifoveal exudative vascular anomalous complex(PEVAC).METHODS: A retrospective case analysis. There were 11 patients(11 eyes)diagnosed as PEVAC by multi-modal imaging in our hospital included in this study from February 2021 to F...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Press of International Journal of Ophthalmology (IJO PRESS)
2022-09-01
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| Series: | Guoji Yanke Zazhi |
| Subjects: | |
| Online Access: | http://ies.ijo.cn/cn_publish/2022/9/202209031.pdf |
| _version_ | 1811187661130432512 |
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| author | Ting-Ting Yang Yue Zhao Jin Yao |
| author_facet | Ting-Ting Yang Yue Zhao Jin Yao |
| author_sort | Ting-Ting Yang |
| collection | DOAJ |
| description | AIM: To observe the imaging characteristics of multi-modal imaging in perifoveal exudative vascular anomalous complex(PEVAC).METHODS: A retrospective case analysis. There were 11 patients(11 eyes)diagnosed as PEVAC by multi-modal imaging in our hospital included in this study from February 2021 to February 2022. All patients underwent the examinations of best corrected visual acuity(BCVA), fundus photography, fluorescein fundus angiography(FFA), spectral-domain optical coherence tomography(SD-OCT)and optical coherence tomography angiography(OCTA).RESULTS: On fundus examination, six out of eleven eyes presented as a unilateral and isolated lesion with diameter ≥150μm, five out of eleven eyes presented as multiple lesions(ranging from 2 to 4)and the diameter of each lesion <150μm, seven eyes with retinal edema and/or hard exudation. FFA revealed an oval-like hyper-fluorescent lesion of parafoveal in the late phase with enhancement but no leakage. Late peripheral telangiectasia leakage is seen with oedema. OCTA examination revealed a parafoveal small mass hyper-reflex showed aneurysmal dilation in the superficial and deep capillary, and capillary rarefaction was observed around the lesion. B-scan showed strong blood flow signal inside. Anti-vascular endothelial growth factor(VEGF)therapy was performed in 4 patients with macular edema. However, there was no notable improvement after treatment.CONCLUSION: Multi-modal imaging can help confirm the diagnosis and differential diagnosis of PEVAC, there is a poorly response to anti-VEGF therapy. |
| first_indexed | 2024-04-11T14:05:59Z |
| format | Article |
| id | doaj.art-8a63364135704d2ab769070178f97ac4 |
| institution | Directory Open Access Journal |
| issn | 1672-5123 |
| language | English |
| last_indexed | 2024-04-11T14:05:59Z |
| publishDate | 2022-09-01 |
| publisher | Press of International Journal of Ophthalmology (IJO PRESS) |
| record_format | Article |
| series | Guoji Yanke Zazhi |
| spelling | doaj.art-8a63364135704d2ab769070178f97ac42022-12-22T04:19:53ZengPress of International Journal of Ophthalmology (IJO PRESS)Guoji Yanke Zazhi1672-51232022-09-012291573157710.3980/j.issn.1672-5123.2022.9.31202209031Parafoveal exudative vascular anomalous complex and its characteristics of multi-modal imaging in 11 casesTing-Ting Yang0Yue Zhao1Jin Yao2The Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu Province, ChinaThe Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu Province, ChinaThe Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210000, Jiangsu Province, ChinaAIM: To observe the imaging characteristics of multi-modal imaging in perifoveal exudative vascular anomalous complex(PEVAC).METHODS: A retrospective case analysis. There were 11 patients(11 eyes)diagnosed as PEVAC by multi-modal imaging in our hospital included in this study from February 2021 to February 2022. All patients underwent the examinations of best corrected visual acuity(BCVA), fundus photography, fluorescein fundus angiography(FFA), spectral-domain optical coherence tomography(SD-OCT)and optical coherence tomography angiography(OCTA).RESULTS: On fundus examination, six out of eleven eyes presented as a unilateral and isolated lesion with diameter ≥150μm, five out of eleven eyes presented as multiple lesions(ranging from 2 to 4)and the diameter of each lesion <150μm, seven eyes with retinal edema and/or hard exudation. FFA revealed an oval-like hyper-fluorescent lesion of parafoveal in the late phase with enhancement but no leakage. Late peripheral telangiectasia leakage is seen with oedema. OCTA examination revealed a parafoveal small mass hyper-reflex showed aneurysmal dilation in the superficial and deep capillary, and capillary rarefaction was observed around the lesion. B-scan showed strong blood flow signal inside. Anti-vascular endothelial growth factor(VEGF)therapy was performed in 4 patients with macular edema. However, there was no notable improvement after treatment.CONCLUSION: Multi-modal imaging can help confirm the diagnosis and differential diagnosis of PEVAC, there is a poorly response to anti-VEGF therapy.http://ies.ijo.cn/cn_publish/2022/9/202209031.pdfperifoveal exudative vascular anomalous complexretinal diseases/diagnosismultimodal imaging examination |
| spellingShingle | Ting-Ting Yang Yue Zhao Jin Yao Parafoveal exudative vascular anomalous complex and its characteristics of multi-modal imaging in 11 cases Guoji Yanke Zazhi perifoveal exudative vascular anomalous complex retinal diseases/diagnosis multimodal imaging examination |
| title | Parafoveal exudative vascular anomalous complex and its characteristics of multi-modal imaging in 11 cases |
| title_full | Parafoveal exudative vascular anomalous complex and its characteristics of multi-modal imaging in 11 cases |
| title_fullStr | Parafoveal exudative vascular anomalous complex and its characteristics of multi-modal imaging in 11 cases |
| title_full_unstemmed | Parafoveal exudative vascular anomalous complex and its characteristics of multi-modal imaging in 11 cases |
| title_short | Parafoveal exudative vascular anomalous complex and its characteristics of multi-modal imaging in 11 cases |
| title_sort | parafoveal exudative vascular anomalous complex and its characteristics of multi modal imaging in 11 cases |
| topic | perifoveal exudative vascular anomalous complex retinal diseases/diagnosis multimodal imaging examination |
| url | http://ies.ijo.cn/cn_publish/2022/9/202209031.pdf |
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