Peripheral nerve block with a high concentration of tetracaine dissolved in bupivacaine for intractable post-herpetic itch: a case report

Abstract Background Post-herpetic itch (PHI) is a neuropathic itch syndrome following herpes zoster. It has been reported that PHI is occasionally sufficiently severe to compromise patients’ quality of life and frequently refractory to treatment. Here, we present a case of severe chronic PHI success...

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Main Authors: Daiki Yamanaka, Takashi Kawano, Marie Shigematsu-Locatelli, Atsushi Nishigaki, Sonoe Kitamura, Bun Aoyama, Hiroki Tateiwa, Noriko Kitaoka, Masataka Yokoyama
Format: Article
Language:English
Published: SpringerOpen 2016-12-01
Series:JA Clinical Reports
Subjects:
Online Access:http://link.springer.com/article/10.1186/s40981-016-0069-y
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author Daiki Yamanaka
Takashi Kawano
Marie Shigematsu-Locatelli
Atsushi Nishigaki
Sonoe Kitamura
Bun Aoyama
Hiroki Tateiwa
Noriko Kitaoka
Masataka Yokoyama
author_facet Daiki Yamanaka
Takashi Kawano
Marie Shigematsu-Locatelli
Atsushi Nishigaki
Sonoe Kitamura
Bun Aoyama
Hiroki Tateiwa
Noriko Kitaoka
Masataka Yokoyama
author_sort Daiki Yamanaka
collection DOAJ
description Abstract Background Post-herpetic itch (PHI) is a neuropathic itch syndrome following herpes zoster. It has been reported that PHI is occasionally sufficiently severe to compromise patients’ quality of life and frequently refractory to treatment. Here, we present a case of severe chronic PHI successfully treated with supraorbital nerve block using a high concentration of tetracaine dissolved in bupivacaine. Case presentation An 82-year-old man presented with severe chronic itching in the ophthalmic branch of the left trigeminal nerve dermatome, following acute herpes zoster. The patient’s itching was unresponsive to usual medical treatments for PHI including antiepileptic drugs, topical capsaicin cream, and supraorbital nerve radiofrequency thermo-coagulation. Topical lidocaine cream could relieve the itching, but could not provide long-term relief of itching and thus failed to achieve a satisfactory result. After these conventional treatments, left supraorbital nerve block using 4% tetracaine dissolved with 0.5% bupivacaine was conducted. Afterwards, the patient experienced long-lasting resolution of the itching with improvement of sleep disturbance. A transient, mild edema of the eyelids occurred, but there were no other complications. Conclusions Peripheral nerve block using 4% tetracaine dissolved with 0.5% bupivacaine was beneficial in relieving PHI in the ophthalmic division of the trigeminal nerve.
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spelling doaj.art-8a659373bdcf418980299db20c6e1cea2022-12-21T18:10:35ZengSpringerOpenJA Clinical Reports2363-90242016-12-01211410.1186/s40981-016-0069-yPeripheral nerve block with a high concentration of tetracaine dissolved in bupivacaine for intractable post-herpetic itch: a case reportDaiki Yamanaka0Takashi Kawano1Marie Shigematsu-Locatelli2Atsushi Nishigaki3Sonoe Kitamura4Bun Aoyama5Hiroki Tateiwa6Noriko Kitaoka7Masataka Yokoyama8Department of Anesthesiology and Intensive Care Medicine, Kochi Medical SchoolDepartment of Anesthesiology and Intensive Care Medicine, Kochi Medical SchoolDepartment of Anesthesiology and Intensive Care Medicine, Kochi Medical SchoolDepartment of Anesthesiology and Intensive Care Medicine, Kochi Medical SchoolDepartment of Anesthesiology and Intensive Care Medicine, Kochi Medical SchoolDepartment of Anesthesiology and Intensive Care Medicine, Kochi Medical SchoolDepartment of Anesthesiology and Intensive Care Medicine, Kochi Medical SchoolDepartment of Anesthesiology and Intensive Care Medicine, Kochi Medical SchoolDepartment of Anesthesiology and Intensive Care Medicine, Kochi Medical SchoolAbstract Background Post-herpetic itch (PHI) is a neuropathic itch syndrome following herpes zoster. It has been reported that PHI is occasionally sufficiently severe to compromise patients’ quality of life and frequently refractory to treatment. Here, we present a case of severe chronic PHI successfully treated with supraorbital nerve block using a high concentration of tetracaine dissolved in bupivacaine. Case presentation An 82-year-old man presented with severe chronic itching in the ophthalmic branch of the left trigeminal nerve dermatome, following acute herpes zoster. The patient’s itching was unresponsive to usual medical treatments for PHI including antiepileptic drugs, topical capsaicin cream, and supraorbital nerve radiofrequency thermo-coagulation. Topical lidocaine cream could relieve the itching, but could not provide long-term relief of itching and thus failed to achieve a satisfactory result. After these conventional treatments, left supraorbital nerve block using 4% tetracaine dissolved with 0.5% bupivacaine was conducted. Afterwards, the patient experienced long-lasting resolution of the itching with improvement of sleep disturbance. A transient, mild edema of the eyelids occurred, but there were no other complications. Conclusions Peripheral nerve block using 4% tetracaine dissolved with 0.5% bupivacaine was beneficial in relieving PHI in the ophthalmic division of the trigeminal nerve.http://link.springer.com/article/10.1186/s40981-016-0069-yPost-herpetic itchPeripheral nerve blockTetracaine
spellingShingle Daiki Yamanaka
Takashi Kawano
Marie Shigematsu-Locatelli
Atsushi Nishigaki
Sonoe Kitamura
Bun Aoyama
Hiroki Tateiwa
Noriko Kitaoka
Masataka Yokoyama
Peripheral nerve block with a high concentration of tetracaine dissolved in bupivacaine for intractable post-herpetic itch: a case report
JA Clinical Reports
Post-herpetic itch
Peripheral nerve block
Tetracaine
title Peripheral nerve block with a high concentration of tetracaine dissolved in bupivacaine for intractable post-herpetic itch: a case report
title_full Peripheral nerve block with a high concentration of tetracaine dissolved in bupivacaine for intractable post-herpetic itch: a case report
title_fullStr Peripheral nerve block with a high concentration of tetracaine dissolved in bupivacaine for intractable post-herpetic itch: a case report
title_full_unstemmed Peripheral nerve block with a high concentration of tetracaine dissolved in bupivacaine for intractable post-herpetic itch: a case report
title_short Peripheral nerve block with a high concentration of tetracaine dissolved in bupivacaine for intractable post-herpetic itch: a case report
title_sort peripheral nerve block with a high concentration of tetracaine dissolved in bupivacaine for intractable post herpetic itch a case report
topic Post-herpetic itch
Peripheral nerve block
Tetracaine
url http://link.springer.com/article/10.1186/s40981-016-0069-y
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