P442: DDX41 GERMLINE VARIANTS: POPULATION PREVALENCE, SIGNIFICANCE AND LEUKEMIC EVOLUTION - Sruthi Cheloor Kovilakam; Muxin Gu; William G. Dunn; Ludovica Marando; Clea Barcena; Serena Nik Zainal; Irina Mohorianu; Siddhartha P. Kar; Margarete A. Fabre; Pedro M. Quiros; George S. Vassiliou (HemaSphere, 2023)