Catabolism of the Last Two Steroid Rings in <italic toggle="yes">Mycobacterium tuberculosis</italic> and Other Bacteria

Catabolism of the Last Two Steroid Rings in <italic toggle="yes">Mycobacterium tuberculosis</italic> and Other Bacteria

ABSTRACT Most mycolic acid-containing actinobacteria and some proteobacteria use steroids as growth substrates, but the catabolism of the last two steroid rings has yet to be elucidated. In Mycobacterium tuberculosis, this pathway includes virulence determinants and has been proposed to be encoded b...

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Bibliographic Details
Main Authors: Adam M. Crowe, Israël Casabon, Kirstin L. Brown, Jie Liu, Jennifer Lian, Jason C. Rogalski, Timothy E. Hurst, Victor Snieckus, Leonard J. Foster, Lindsay D. Eltis
Format: Article
Language:English
Published: American Society for Microbiology 2017-05-01
Series:mBio
Subjects:
CoA thioester
Mycobacterium tuberculosis
catabolism
cholesterol
ring opening
Online Access:https://journals.asm.org/doi/10.1128/mBio.00321-17

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