Systematic review comparing LABA, olodaterol, and indacaterol: limitations
James F Donohue Pulmonary Diseases and Critical Care Medicine, UNC School of Medicine, Chapel Hill, NC, USA Dear editor Roskell et al present a systematic review comparing the long-acting beta2 agonists (LABA), olodaterol, and indacaterol in the July edition of the Inter...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2014-12-01
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| Series: | International Journal of COPD |
| Online Access: | http://www.dovepress.com/systematic-review-comparing-laba-olodaterol-and-indacaterol-limitation-peer-reviewed-article-COPD |
| _version_ | 1831769701910315008 |
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| author | Donohue JF |
| author_facet | Donohue JF |
| author_sort | Donohue JF |
| collection | DOAJ |
| description | James F Donohue Pulmonary Diseases and Critical Care Medicine, UNC School of Medicine, Chapel Hill, NC, USA Dear editor Roskell et al present a systematic review comparing the long-acting beta2 agonists (LABA), olodaterol, and indacaterol in the July edition of the International Journal of Chronic Obstructive Pulmonary Disease.1 The end-points compared for the two LABAs were: change from baseline in trough forced expiratory volume in 1 second (FEV1) at week 12; quality of life analyzed by change from baseline in St George’s Respiratory Quotient (SGRQ; total score and proportion of responders) at week 12; transition dyspnea index (TDI), analyzed by change from baseline at week 12; use of rescue medication, analyzed by change from baseline in average number of puffs per day; and proportion of patients experiencing at least one exacerbation, analyzed in trials with a treatment duration of 24 weeks or longer reporting data for this outcome. The authors conclude that olodaterol and indacaterol have similar efficacy in patients with COPD. Read the original article |
| first_indexed | 2024-12-22T07:25:59Z |
| format | Article |
| id | doaj.art-8a6aab852d1f43668b7354e17c5e4135 |
| institution | Directory Open Access Journal |
| issn | 1178-2005 |
| language | English |
| last_indexed | 2024-12-22T07:25:59Z |
| publishDate | 2014-12-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | International Journal of COPD |
| spelling | doaj.art-8a6aab852d1f43668b7354e17c5e41352022-12-21T18:34:09ZengDove Medical PressInternational Journal of COPD1178-20052014-12-012014default1331133519436Systematic review comparing LABA, olodaterol, and indacaterol: limitationsDonohue JFJames F Donohue Pulmonary Diseases and Critical Care Medicine, UNC School of Medicine, Chapel Hill, NC, USA Dear editor Roskell et al present a systematic review comparing the long-acting beta2 agonists (LABA), olodaterol, and indacaterol in the July edition of the International Journal of Chronic Obstructive Pulmonary Disease.1 The end-points compared for the two LABAs were: change from baseline in trough forced expiratory volume in 1 second (FEV1) at week 12; quality of life analyzed by change from baseline in St George’s Respiratory Quotient (SGRQ; total score and proportion of responders) at week 12; transition dyspnea index (TDI), analyzed by change from baseline at week 12; use of rescue medication, analyzed by change from baseline in average number of puffs per day; and proportion of patients experiencing at least one exacerbation, analyzed in trials with a treatment duration of 24 weeks or longer reporting data for this outcome. The authors conclude that olodaterol and indacaterol have similar efficacy in patients with COPD. Read the original article http://www.dovepress.com/systematic-review-comparing-laba-olodaterol-and-indacaterol-limitation-peer-reviewed-article-COPD |
| spellingShingle | Donohue JF Systematic review comparing LABA, olodaterol, and indacaterol: limitations International Journal of COPD |
| title | Systematic review comparing LABA, olodaterol, and indacaterol: limitations |
| title_full | Systematic review comparing LABA, olodaterol, and indacaterol: limitations |
| title_fullStr | Systematic review comparing LABA, olodaterol, and indacaterol: limitations |
| title_full_unstemmed | Systematic review comparing LABA, olodaterol, and indacaterol: limitations |
| title_short | Systematic review comparing LABA, olodaterol, and indacaterol: limitations |
| title_sort | systematic review comparing laba olodaterol and indacaterol limitations |
| url | http://www.dovepress.com/systematic-review-comparing-laba-olodaterol-and-indacaterol-limitation-peer-reviewed-article-COPD |
| work_keys_str_mv | AT donohuejf systematicreviewcomparinglabaolodaterolandindacaterollimitations |