The Association Between Arterial Stiffness and Muscle Indices Among Healthy Subjects and Subjects With Cardiovascular Risk Factors: An Evidence-Based Review
Skeletal muscle is one of the major tissues in the body and is important for performing daily physical activity. Previous studies suggest that vascular dysfunction contributes to reduced skeletal muscle mass. However, the association between vascular dysfunction and muscle mass, muscle strength and...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-11-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2021.742338/full |
| _version_ | 1818833845837889536 |
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| author | Amilia Aminuddin Muhammad Fakhrurrazi Noor Hashim Nur Aina Syazana Mohd Zaberi Lee Zheng Wei Beh Ching Chu Nur Amalina Jamaludin Norizam Salamt Nur Aishah Che Roos Azizah Ugusman |
| author_facet | Amilia Aminuddin Muhammad Fakhrurrazi Noor Hashim Nur Aina Syazana Mohd Zaberi Lee Zheng Wei Beh Ching Chu Nur Amalina Jamaludin Norizam Salamt Nur Aishah Che Roos Azizah Ugusman |
| author_sort | Amilia Aminuddin |
| collection | DOAJ |
| description | Skeletal muscle is one of the major tissues in the body and is important for performing daily physical activity. Previous studies suggest that vascular dysfunction contributes to reduced skeletal muscle mass. However, the association between vascular dysfunction and muscle mass, muscle strength and muscle flexibility are less established. Therefore, the focus of this review was to investigate the association between arterial stiffness (AS) which is a marker of vascular function, and muscle indices among healthy and those with cardiovascular risk factors. Three databases were used to search for relevant studies. These keywords were used: “arterial stiffness” OR “vascular stiffness” OR “aortic stiffness” OR “pulse wave velocity” OR “carotid femoral pulse wave velocity” OR “pulse wave analysis” AND “muscle” OR “skeletal” OR “flexibility” OR “range of motion” OR “articular” OR “arthrometry” OR “strength” OR “hand strength” OR “pinch strength” OR “mass” OR “lean” OR “body composition.” The criteria were; (1) original, full-text articles, (2) articles written in English language, (3) human studies involving healthy adults and/or adults with cardiovascular disease (CVD) or CVD risk factors (4) articles that reported the relationship between AS (measured as carotid-femoral pulse wave velocity or brachial-ankle pulse wave velocity) and muscle indices (measured as muscle mass, muscle flexibility and muscle strength) after adjusting for relevant confounders. The search identified 2295 articles published between 1971 and June 2021. Only 17 articles fulfilled the criteria. Two studies showed an inverse association between AS and muscle strength in healthy subjects, whereas in subjects with CVD risk factors, five out of seven studies found an inverse correlation between the two parameters. Eleven studies showed an inverse association between AS and muscle mass in subjects with CVD and CVD risk factors. The association between AS and muscle flexibility was not studied in any of the articles reviewed. In conclusion, there is an inverse correlation between muscle indices and AS in healthy adults and those with CVD or CVD risk factors. However, most of the studies were cross-sectional studies, hence the need for future prospective studies to address this issue. |
| first_indexed | 2024-12-19T02:25:24Z |
| format | Article |
| id | doaj.art-8a6d9075ea9f4295addc1340f87d2009 |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-12-19T02:25:24Z |
| publishDate | 2021-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-8a6d9075ea9f4295addc1340f87d20092022-12-21T20:39:57ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2021-11-011210.3389/fphys.2021.742338742338The Association Between Arterial Stiffness and Muscle Indices Among Healthy Subjects and Subjects With Cardiovascular Risk Factors: An Evidence-Based ReviewAmilia Aminuddin0Muhammad Fakhrurrazi Noor Hashim1Nur Aina Syazana Mohd Zaberi2Lee Zheng Wei3Beh Ching Chu4Nur Amalina Jamaludin5Norizam Salamt6Nur Aishah Che Roos7Azizah Ugusman8Department of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Cheras, MalaysiaDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Cheras, MalaysiaDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Cheras, MalaysiaDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Cheras, MalaysiaDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Cheras, MalaysiaDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Cheras, MalaysiaDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Cheras, MalaysiaFaculty of Medicine and Defence Health, National Defence University of Malaysia, Kem Sungai Besi, MalaysiaDepartment of Physiology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Cheras, MalaysiaSkeletal muscle is one of the major tissues in the body and is important for performing daily physical activity. Previous studies suggest that vascular dysfunction contributes to reduced skeletal muscle mass. However, the association between vascular dysfunction and muscle mass, muscle strength and muscle flexibility are less established. Therefore, the focus of this review was to investigate the association between arterial stiffness (AS) which is a marker of vascular function, and muscle indices among healthy and those with cardiovascular risk factors. Three databases were used to search for relevant studies. These keywords were used: “arterial stiffness” OR “vascular stiffness” OR “aortic stiffness” OR “pulse wave velocity” OR “carotid femoral pulse wave velocity” OR “pulse wave analysis” AND “muscle” OR “skeletal” OR “flexibility” OR “range of motion” OR “articular” OR “arthrometry” OR “strength” OR “hand strength” OR “pinch strength” OR “mass” OR “lean” OR “body composition.” The criteria were; (1) original, full-text articles, (2) articles written in English language, (3) human studies involving healthy adults and/or adults with cardiovascular disease (CVD) or CVD risk factors (4) articles that reported the relationship between AS (measured as carotid-femoral pulse wave velocity or brachial-ankle pulse wave velocity) and muscle indices (measured as muscle mass, muscle flexibility and muscle strength) after adjusting for relevant confounders. The search identified 2295 articles published between 1971 and June 2021. Only 17 articles fulfilled the criteria. Two studies showed an inverse association between AS and muscle strength in healthy subjects, whereas in subjects with CVD risk factors, five out of seven studies found an inverse correlation between the two parameters. Eleven studies showed an inverse association between AS and muscle mass in subjects with CVD and CVD risk factors. The association between AS and muscle flexibility was not studied in any of the articles reviewed. In conclusion, there is an inverse correlation between muscle indices and AS in healthy adults and those with CVD or CVD risk factors. However, most of the studies were cross-sectional studies, hence the need for future prospective studies to address this issue.https://www.frontiersin.org/articles/10.3389/fphys.2021.742338/fullarterial stiffnesspulse wave velocitymuscle massmuscle strengthmuscle flexibilitycardiovascular |
| spellingShingle | Amilia Aminuddin Muhammad Fakhrurrazi Noor Hashim Nur Aina Syazana Mohd Zaberi Lee Zheng Wei Beh Ching Chu Nur Amalina Jamaludin Norizam Salamt Nur Aishah Che Roos Azizah Ugusman The Association Between Arterial Stiffness and Muscle Indices Among Healthy Subjects and Subjects With Cardiovascular Risk Factors: An Evidence-Based Review Frontiers in Physiology arterial stiffness pulse wave velocity muscle mass muscle strength muscle flexibility cardiovascular |
| title | The Association Between Arterial Stiffness and Muscle Indices Among Healthy Subjects and Subjects With Cardiovascular Risk Factors: An Evidence-Based Review |
| title_full | The Association Between Arterial Stiffness and Muscle Indices Among Healthy Subjects and Subjects With Cardiovascular Risk Factors: An Evidence-Based Review |
| title_fullStr | The Association Between Arterial Stiffness and Muscle Indices Among Healthy Subjects and Subjects With Cardiovascular Risk Factors: An Evidence-Based Review |
| title_full_unstemmed | The Association Between Arterial Stiffness and Muscle Indices Among Healthy Subjects and Subjects With Cardiovascular Risk Factors: An Evidence-Based Review |
| title_short | The Association Between Arterial Stiffness and Muscle Indices Among Healthy Subjects and Subjects With Cardiovascular Risk Factors: An Evidence-Based Review |
| title_sort | association between arterial stiffness and muscle indices among healthy subjects and subjects with cardiovascular risk factors an evidence based review |
| topic | arterial stiffness pulse wave velocity muscle mass muscle strength muscle flexibility cardiovascular |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2021.742338/full |
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