CMV Disease of Upper GI Tract in Immunocompetent Host: Two Case Reports and Brief Review of Literature

Gastrointestinal cytomegalovirus (GI-CMV) infection is well-reported in immunocompromised individuals and those on chemotherapy or other immunosuppressive medications. Rarely, CMV infection of gastrointestinal tract (GIT) occurs in immunocompetent individuals. Colon is the most common site of GI inv...

Full description

Bibliographic Details
Main Authors: Nikhil Mahajan, Aproo Sharma, Mukesh Nasa, Lipika Lipi, Rini Sharma, Navleen Arora, Balwinder Singh
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2020-12-01
Series:Journal of Digestive Endoscopy
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1716449
_version_ 1818976596589019136
author Nikhil Mahajan
Aproo Sharma
Mukesh Nasa
Lipika Lipi
Rini Sharma
Navleen Arora
Balwinder Singh
author_facet Nikhil Mahajan
Aproo Sharma
Mukesh Nasa
Lipika Lipi
Rini Sharma
Navleen Arora
Balwinder Singh
author_sort Nikhil Mahajan
collection DOAJ
description Gastrointestinal cytomegalovirus (GI-CMV) infection is well-reported in immunocompromised individuals and those on chemotherapy or other immunosuppressive medications. Rarely, CMV infection of gastrointestinal tract (GIT) occurs in immunocompetent individuals. Colon is the most common site of GI involvement with CMV. However, in immunocompetent individuals, upper GIT involvement is more common. Clinical spectrum of GI-CMV disease is variable and depends on the location and severity of the disease. Prompt diagnosis and treatment aids in reducing morbidity and mortality related to CMV involvement in GI tract. We present two interesting cases of CMV-induced GI ulcers in immunocompetent individuals with brief review of diagnostic and treatment challenges associated with CMV disease in immunocompetent individuals.
first_indexed 2024-12-20T16:14:22Z
format Article
id doaj.art-8a7047dc4d4e420385d08a2ca73b8d9c
institution Directory Open Access Journal
issn 0976-5042
0976-5050
language English
last_indexed 2024-12-20T16:14:22Z
publishDate 2020-12-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Journal of Digestive Endoscopy
spelling doaj.art-8a7047dc4d4e420385d08a2ca73b8d9c2022-12-21T19:33:52ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Digestive Endoscopy0976-50420976-50502020-12-01120424925210.1055/s-0040-1716449CMV Disease of Upper GI Tract in Immunocompetent Host: Two Case Reports and Brief Review of LiteratureNikhil Mahajan0Aproo Sharma1Mukesh Nasa2Lipika Lipi3Rini Sharma4Navleen Arora5Balwinder Singh6Department of Gastroenterology, Shrimann Hospital, Jalandhar, Punjab, IndiaDepartment of Pathology, AFCME, New Delhi, IndiaDepartment of Gastroenterology, Shrimann Hospital, Jalandhar, Punjab, IndiaDepartment of Gastro-Pathology, Medanta-The Medicity, Gurugram, Haryana, IndiaDepartment of Pathology, ASCOMS, Jammu, J & K, IndiaDepartment of Pathology, Shrimann Hospital, Jalandhar, Punjab, IndiaDepartment of Gastroenterology, Shrimann Hospital, Jalandhar, Punjab, IndiaGastrointestinal cytomegalovirus (GI-CMV) infection is well-reported in immunocompromised individuals and those on chemotherapy or other immunosuppressive medications. Rarely, CMV infection of gastrointestinal tract (GIT) occurs in immunocompetent individuals. Colon is the most common site of GI involvement with CMV. However, in immunocompetent individuals, upper GIT involvement is more common. Clinical spectrum of GI-CMV disease is variable and depends on the location and severity of the disease. Prompt diagnosis and treatment aids in reducing morbidity and mortality related to CMV involvement in GI tract. We present two interesting cases of CMV-induced GI ulcers in immunocompetent individuals with brief review of diagnostic and treatment challenges associated with CMV disease in immunocompetent individuals.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1716449cytomegalovirus (cmv)esophageal ulcergastric ulcerimmunocompetentupper gastrointestinal tract
spellingShingle Nikhil Mahajan
Aproo Sharma
Mukesh Nasa
Lipika Lipi
Rini Sharma
Navleen Arora
Balwinder Singh
CMV Disease of Upper GI Tract in Immunocompetent Host: Two Case Reports and Brief Review of Literature
Journal of Digestive Endoscopy
cytomegalovirus (cmv)
esophageal ulcer
gastric ulcer
immunocompetent
upper gastrointestinal tract
title CMV Disease of Upper GI Tract in Immunocompetent Host: Two Case Reports and Brief Review of Literature
title_full CMV Disease of Upper GI Tract in Immunocompetent Host: Two Case Reports and Brief Review of Literature
title_fullStr CMV Disease of Upper GI Tract in Immunocompetent Host: Two Case Reports and Brief Review of Literature
title_full_unstemmed CMV Disease of Upper GI Tract in Immunocompetent Host: Two Case Reports and Brief Review of Literature
title_short CMV Disease of Upper GI Tract in Immunocompetent Host: Two Case Reports and Brief Review of Literature
title_sort cmv disease of upper gi tract in immunocompetent host two case reports and brief review of literature
topic cytomegalovirus (cmv)
esophageal ulcer
gastric ulcer
immunocompetent
upper gastrointestinal tract
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1716449
work_keys_str_mv AT nikhilmahajan cmvdiseaseofuppergitractinimmunocompetenthosttwocasereportsandbriefreviewofliterature
AT aproosharma cmvdiseaseofuppergitractinimmunocompetenthosttwocasereportsandbriefreviewofliterature
AT mukeshnasa cmvdiseaseofuppergitractinimmunocompetenthosttwocasereportsandbriefreviewofliterature
AT lipikalipi cmvdiseaseofuppergitractinimmunocompetenthosttwocasereportsandbriefreviewofliterature
AT rinisharma cmvdiseaseofuppergitractinimmunocompetenthosttwocasereportsandbriefreviewofliterature
AT navleenarora cmvdiseaseofuppergitractinimmunocompetenthosttwocasereportsandbriefreviewofliterature
AT balwindersingh cmvdiseaseofuppergitractinimmunocompetenthosttwocasereportsandbriefreviewofliterature