Advanced brain aging in Parkinson’s disease with cognitive impairment

Advanced brain aging in Parkinson’s disease with cognitive impairment

Abstract Patients with Parkinson’s disease and cognitive impairment (PD-CI) deteriorate faster than those without cognitive impairment (PD-NCI), suggesting an underlying difference in the neurodegeneration process. We aimed to verify brain age differences in PD-CI and PD-NCI and their clinical signi...

Full description

Bibliographic Details
Main Authors:	Chang-Le Chen, Shao-Ying Cheng, Leila Montaser-Kouhsari, Wen-Chao Wu, Yung-Chin Hsu, Chun-Hwei Tai, Wen-Yih Isaac Tseng, Ming-Che Kuo, Ruey-Meei Wu
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-03-01
Series:	npj Parkinson's Disease
Online Access:	https://doi.org/10.1038/s41531-024-00673-7

Similar Items

Recent advances in using diffusion tensor imaging to study white matter alterations in Parkinson’s disease: A mini review
by: Yao-Chia Shih, et al.
Published: (2023-02-01)

Mutational analysis of angiogenin gene in Parkinson's disease.
by: Meng-Ling Chen, et al.
Published: (2014-01-01)

FastEval Parkinsonism: an instant deep learning–assisted video-based online system for Parkinsonian motor symptom evaluation
by: Yu-Yuan Yang, et al.
Published: (2024-02-01)

Mild cognitive impairment in patients with Parkinson’s disease: An updated mini-review and future outlook
by: Rwei-Ling Yu, et al.
Published: (2022-09-01)

Prosaposin variants in sporadic, familial, and early-onset Parkinson's disease: a Taiwanese case–control study and meta-analysis
by: Ming-Che Kuo, et al.
Published: (2024-01-01)

Homozygous mutation of the LRRK2 ROC domain as a novel genetic model of parkinsonism
by: Meng-Ling Chen, et al.
Published: (2022-08-01)

Publisher Correction: Platelet abnormalities in patients with Parkinson's disease undergoing preoperative evaluation for deep brain stimulation
by: Sheng-Che Chou, et al.
Published: (2022-10-01)

Interactions of COMT and ALDH2 Genetic Polymorphisms on Symptoms of Parkinson’s Disease
by: Rwei-Ling Yu, et al.
Published: (2021-03-01)

Alpha-Synuclein and Cognitive Decline in Parkinson Disease
by: Tian-Sin Fan, et al.
Published: (2021-11-01)

Remote assessment of cognition in Parkinson’s disease and Cerebellar Ataxia: the MoCA test in English and Hebrew
by: Sharon Binoy, et al.
Published: (2024-01-01)

Corrigendum: Remote assessment of cognition in Parkinson's disease and cerebellar ataxia: the MoCA test in English and Hebrew
by: Sharon Binoy, et al.
Published: (2024-04-01)

Plasma miR-203a-3p as a Novel Predictor of Dementia in Patients with Parkinson’s Disease
by: Ya-Fang Hsu, et al.
Published: (2024-03-01)

Dual-task walking improvement with enhanced kinesthetic awareness in Parkinson’s disease with mild gait impairment: EEG connectivity and clinical implication
by: Cheng-Ya Huang, et al.
Published: (2022-11-01)

Plasma extracellular vesicle tau, β-amyloid, and α-synuclein and the progression of Parkinson’s disease: a follow-up study
by: Lung Chan, et al.
Published: (2023-01-01)

Online cognitive testing in Parkinson’s disease: advantages and challenges
by: Sharon Binoy, et al.
Published: (2024-04-01)

Ophthalmologic problems correlates with cognitive impairment in patients with Parkinson's disease
by: Chao Zhang, et al.
Published: (2022-10-01)

Association between GRN rs5848 polymorphism and Parkinson's disease in Taiwanese population.
by: Kuo-Hsuan Chang, et al.
Published: (2013-01-01)

Bioactive self-healing hydrogel based on tannic acid modified gold nano-crosslinker as an injectable brain implant for treating Parkinson’s disease
by: Junpeng Xu, et al.
Published: (2023-02-01)

MRI of structured-based ventricular mechanics
by: Tseng, Wen-Yih Isaac, 1957-
Published: (2009)

Cerebellar deep brain stimulation for movement disorders
by: Chun-Hwei Tai, et al.
Published: (2022-12-01)

Association of AXIN1 With Parkinson’s Disease in a Taiwanese Population
by: Hwa-Shin Fang, et al.
Published: (2022-01-01)

UQCRC1 variants in early-onset and familial Parkinson's disease in a Taiwanese cohort
by: Ting-Wei Liao, et al.
Published: (2022-12-01)

Inhibition of acetyl-CoA carboxylase impaired tubulin palmitoylation and induced spindle abnormalities
by: Chieh-Ting Fang, et al.
Published: (2023-01-01)

Sparse solution of fiber orientation distribution function by diffusion decomposition.
by: Fang-Cheng Yeh, et al.
Published: (2013-01-01)

Microstructural but not macrostructural cortical degeneration occurs in Parkinson’s disease with mild cognitive impairment
by: Xueqin Bai, et al.
Published: (2022-11-01)

IMPAIRED ANTISACCADES IN PARKINSON'S DISEASE
by: Antoniades, C, et al.
Published: (2012)

Impairment in the Intention Formation and Execution Phases of Prospective Memory in Parkinson's Disease
by: Shu-Hong Jia, et al.
Published: (2018-02-01)

Interaction of systemic oxidative stress and mesial temporal network degeneration in Parkinson’s disease with and without cognitive impairment
by: Pi-Ling Chiang, et al.
Published: (2018-09-01)

Salience Network and Depressive Severities in Parkinson’s Disease with Mild Cognitive Impairment: A Structural Covariance Network Analysis
by: Ya-Ting Chang, et al.
Published: (2018-01-01)

Robust dynamic and algebraic state estimation for microgrids: A generalized approach
by: Iraj Pourkeivani, et al.
Published: (2023-10-01)

Cognitive impairment and dementia in parkinson's disease /
Published: (2010)

Cardiovascular Autonomic Impairment in Parkinson Disease
by: Asma'a Khalaf Hamod, et al.
Published: (2019-07-01)

Cardiovascular Autonomic Impairment in Parkinson Disease
by: Asma'a Khalaf Hamod, et al.
Published: (2019-07-01)

Cognitive impairment in patients with Parkinson’s disease
by: I. A. Zhukova, et al.
Published: (2010-08-01)

No-motor impairment in patients with Parkinson’s disease
by: I. A. Zhukova, et al.
Published: (2009-02-01)

Verbal Reasoning Impairment in Parkinson’s Disease
by: Antonina Luca, et al.
Published: (2022-01-01)

Impairment of endothelial function in Parkinson’s disease
by: Branislav Kollár, et al.
Published: (2022-09-01)

Classification of the Multiple Stages of Parkinson’s Disease by a Deep Convolution Neural Network Based on <sup>99m</sup>Tc-TRODAT-1 SPECT Images
by: Shih-Yen Hsu, et al.
Published: (2020-10-01)

Higher serum Lp-PLA2 is associated with cognitive impairment in Parkinson’s disease patients
by: Zubo Wu, et al.
Published: (2024-03-01)

Home-Based Orolingual Exercise Improves the Coordination of Swallowing and Respiration in Early Parkinson Disease: A Quasi-Experimental Before-and-After Exercise Program Study
by: Chin-Man Wang, et al.
Published: (2018-07-01)