A Case of Neurobrucellosis Presenting with Isolated for Brucella spp. in the Broth Specific for Mycobacterium Species

In cerebrospinal fluid (CSF) specimen of a 51-year-old patient suspected of meningitis, standard brucella agglutination test was detected to be 1/128 positive. Also, microscopical and biochemical investigations of CSF specimen revealed 280 leukocytes/mm3 (92% lymphocyte), a normal level of glucose (...

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Main Authors: Hikmet Eda ALIŞKAN, Yusuf Ziya DEMİROĞLU
Format: Article
Language:English
Published: Bilimsel Tip Yayinevi 2014-03-01
Series:Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Subjects:
Online Access:http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2014-19-01-049-053.pdf
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author Hikmet Eda ALIŞKAN
Yusuf Ziya DEMİROĞLU
author_facet Hikmet Eda ALIŞKAN
Yusuf Ziya DEMİROĞLU
author_sort Hikmet Eda ALIŞKAN
collection DOAJ
description In cerebrospinal fluid (CSF) specimen of a 51-year-old patient suspected of meningitis, standard brucella agglutination test was detected to be 1/128 positive. Also, microscopical and biochemical investigations of CSF specimen revealed 280 leukocytes/mm3 (92% lymphocyte), a normal level of glucose (52 mg/dL), and a high level of protein (118 mg/dL). No microorganism was observed in routine bacteriological CSF cultures. Also, there was no microorganism with Gram and Auramine-rhodamine staining. After the decontamination and homogenization process, CSF specimen were inoculated into Mycobacteria Growth Indicator Tube (MGIT) 320 device which was specifically developed for isolation mycobacteria species. The isolate which proliferated in MGIT was identified as Brucella spp. The case was diagnosed and treated as neurobrucellosis. This is the first reported case of Brucella spp. isolation of CSF specimen in BACTEC MGIT system and considered as the pathogen.
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spelling doaj.art-8a717cd129af4b39b6b43d3dfafddb7d2023-02-15T16:11:14ZengBilimsel Tip YayineviFlora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi1300-932X1300-932X2014-03-011914953A Case of Neurobrucellosis Presenting with Isolated for Brucella spp. in the Broth Specific for Mycobacterium SpeciesHikmet Eda ALIŞKAN0Yusuf Ziya DEMİROĞLU1Department of Medical Microbiology, Faculty of Medicine, University of Baskent, Adana, TurkeyDepartment of Infectious Diseases and Clinical Microbiology, Faculty of Medicine, University of Baskent, Adana, TurkeyIn cerebrospinal fluid (CSF) specimen of a 51-year-old patient suspected of meningitis, standard brucella agglutination test was detected to be 1/128 positive. Also, microscopical and biochemical investigations of CSF specimen revealed 280 leukocytes/mm3 (92% lymphocyte), a normal level of glucose (52 mg/dL), and a high level of protein (118 mg/dL). No microorganism was observed in routine bacteriological CSF cultures. Also, there was no microorganism with Gram and Auramine-rhodamine staining. After the decontamination and homogenization process, CSF specimen were inoculated into Mycobacteria Growth Indicator Tube (MGIT) 320 device which was specifically developed for isolation mycobacteria species. The isolate which proliferated in MGIT was identified as Brucella spp. The case was diagnosed and treated as neurobrucellosis. This is the first reported case of Brucella spp. isolation of CSF specimen in BACTEC MGIT system and considered as the pathogen.http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2014-19-01-049-053.pdfBrucellosisBrucella
spellingShingle Hikmet Eda ALIŞKAN
Yusuf Ziya DEMİROĞLU
A Case of Neurobrucellosis Presenting with Isolated for Brucella spp. in the Broth Specific for Mycobacterium Species
Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
Brucellosis
Brucella
title A Case of Neurobrucellosis Presenting with Isolated for Brucella spp. in the Broth Specific for Mycobacterium Species
title_full A Case of Neurobrucellosis Presenting with Isolated for Brucella spp. in the Broth Specific for Mycobacterium Species
title_fullStr A Case of Neurobrucellosis Presenting with Isolated for Brucella spp. in the Broth Specific for Mycobacterium Species
title_full_unstemmed A Case of Neurobrucellosis Presenting with Isolated for Brucella spp. in the Broth Specific for Mycobacterium Species
title_short A Case of Neurobrucellosis Presenting with Isolated for Brucella spp. in the Broth Specific for Mycobacterium Species
title_sort case of neurobrucellosis presenting with isolated for brucella spp in the broth specific for mycobacterium species
topic Brucellosis
Brucella
url http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2014-19-01-049-053.pdf
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