Emerging translational strategies and challenges for enhancing regulatory T cell therapy for graft-versus-host disease

Emerging translational strategies and challenges for enhancing regulatory T cell therapy for graft-versus-host disease

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is a curative therapy for many types of cancer. Genetic disparities between donor and host can result in immune-mediated attack of host tissues, known as graft versus host disease (GVHD), a major cause of morbidity and mortality followin...

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Bibliographic Details
Main Authors: Keli L. Hippen, Mehrdad Hefazi, Jemma H. Larson, Bruce R. Blazar
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
tTreg
pTreg
iTreg
CAR
GVHD
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.926550/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.926550/full

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