Formation of a calcium oxalate urethral stone in a 3‐year‐old boy due to hypocitraturia
Introduction Urolithiasis in children is often due to metabolic abnormalities (e.g. hypocitraturia) and hence recurs frequently. Case presentation A 3‐year‐old boy presented with gross hematuria. Computed tomography detected a urethral calculus. The calculus was removed surgically. The stone was com...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2020-03-01
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| Series: | IJU Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/iju5.12140 |
| _version_ | 1811268367480258560 |
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| author | Nobuhisa Kita Yoshiro Nagao Yoshiyuki Nabeshima Ichiro Yamane Masaaki Hirata Kuniya Hatakeyama |
| author_facet | Nobuhisa Kita Yoshiro Nagao Yoshiyuki Nabeshima Ichiro Yamane Masaaki Hirata Kuniya Hatakeyama |
| author_sort | Nobuhisa Kita |
| collection | DOAJ |
| description | Introduction Urolithiasis in children is often due to metabolic abnormalities (e.g. hypocitraturia) and hence recurs frequently. Case presentation A 3‐year‐old boy presented with gross hematuria. Computed tomography detected a urethral calculus. The calculus was removed surgically. The stone was composed of calcium oxalate. Although oxalate and uric acid levels in the urine were within normal ranges, urine calcium was moderately elevated and urine citrate was substantially low. Urinalyses of the parents revealed that the father had acidic hypocitraturic urine, containing oxalate crystals, and the mother had hypercalciuria. Administration of oral citrate acid normalized urine citrate levels and eliminated the oxalate crystals, from the boy and his father. Conclusion Although preventing urolithiasis using oral citrate is common in the adult population, this preventive measure is not well recognized in children, thus warranting further study. |
| first_indexed | 2024-04-12T21:21:39Z |
| format | Article |
| id | doaj.art-8a770b8ba36c45b38585d06e235a92c5 |
| institution | Directory Open Access Journal |
| issn | 2577-171X |
| language | English |
| last_indexed | 2024-04-12T21:21:39Z |
| publishDate | 2020-03-01 |
| publisher | Wiley |
| record_format | Article |
| series | IJU Case Reports |
| spelling | doaj.art-8a770b8ba36c45b38585d06e235a92c52022-12-22T03:16:18ZengWileyIJU Case Reports2577-171X2020-03-0132495210.1002/iju5.12140Formation of a calcium oxalate urethral stone in a 3‐year‐old boy due to hypocitraturiaNobuhisa Kita0Yoshiro Nagao1Yoshiyuki Nabeshima2Ichiro Yamane3Masaaki Hirata4Kuniya Hatakeyama5Department of Pediatrics Fukuoka Tokushukai Hospital Kasuga Fukuoka JapanDepartment of Pediatrics Fukuoka Tokushukai Hospital Kasuga Fukuoka JapanDepartment of Urology Fukuoka Tokushukai Hospital Kasuga Fukuoka JapanDepartment of Pediatrics Fukuoka Tokushukai Hospital Kasuga Fukuoka JapanDepartment of Pediatrics Fukuoka Tokushukai Hospital Kasuga Fukuoka JapanDepartment of Pediatrics Fukuoka Tokushukai Hospital Kasuga Fukuoka JapanIntroduction Urolithiasis in children is often due to metabolic abnormalities (e.g. hypocitraturia) and hence recurs frequently. Case presentation A 3‐year‐old boy presented with gross hematuria. Computed tomography detected a urethral calculus. The calculus was removed surgically. The stone was composed of calcium oxalate. Although oxalate and uric acid levels in the urine were within normal ranges, urine calcium was moderately elevated and urine citrate was substantially low. Urinalyses of the parents revealed that the father had acidic hypocitraturic urine, containing oxalate crystals, and the mother had hypercalciuria. Administration of oral citrate acid normalized urine citrate levels and eliminated the oxalate crystals, from the boy and his father. Conclusion Although preventing urolithiasis using oral citrate is common in the adult population, this preventive measure is not well recognized in children, thus warranting further study.https://doi.org/10.1002/iju5.12140calcium oxalatecitratespediatricsurinary calculiurolithiasis |
| spellingShingle | Nobuhisa Kita Yoshiro Nagao Yoshiyuki Nabeshima Ichiro Yamane Masaaki Hirata Kuniya Hatakeyama Formation of a calcium oxalate urethral stone in a 3‐year‐old boy due to hypocitraturia IJU Case Reports calcium oxalate citrates pediatrics urinary calculi urolithiasis |
| title | Formation of a calcium oxalate urethral stone in a 3‐year‐old boy due to hypocitraturia |
| title_full | Formation of a calcium oxalate urethral stone in a 3‐year‐old boy due to hypocitraturia |
| title_fullStr | Formation of a calcium oxalate urethral stone in a 3‐year‐old boy due to hypocitraturia |
| title_full_unstemmed | Formation of a calcium oxalate urethral stone in a 3‐year‐old boy due to hypocitraturia |
| title_short | Formation of a calcium oxalate urethral stone in a 3‐year‐old boy due to hypocitraturia |
| title_sort | formation of a calcium oxalate urethral stone in a 3 year old boy due to hypocitraturia |
| topic | calcium oxalate citrates pediatrics urinary calculi urolithiasis |
| url | https://doi.org/10.1002/iju5.12140 |
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