Between-Sex Differences in Risk Factors for Cardiovascular Disease among Patients with Myocardial Infarction—A Systematic Review
Between-sex differences in the presentation, risk factors, management, and outcomes of acute myocardial infarction (MI) are well documented. However, as such differences are highly sensitive to cultural and social changes, there is a need to continuously re-evaluate the evidence. The present contemp...
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-08-01
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| Series: | Journal of Clinical Medicine |
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| Online Access: | https://www.mdpi.com/2077-0383/12/15/5163 |
| _version_ | 1797586456739315712 |
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| author | Jack Charles Barton Anna Wozniak Chloe Scott Abhisekh Chatterjee Greg Nathan Titterton Amber Elyse Corrigan Ashvin Kuri Viraj Shah Ian Soh Juan Carlos Kaski |
| author_facet | Jack Charles Barton Anna Wozniak Chloe Scott Abhisekh Chatterjee Greg Nathan Titterton Amber Elyse Corrigan Ashvin Kuri Viraj Shah Ian Soh Juan Carlos Kaski |
| author_sort | Jack Charles Barton |
| collection | DOAJ |
| description | Between-sex differences in the presentation, risk factors, management, and outcomes of acute myocardial infarction (MI) are well documented. However, as such differences are highly sensitive to cultural and social changes, there is a need to continuously re-evaluate the evidence. The present contemporary systematic review assesses the baseline characteristics of men and women presenting to secondary, tertiary, and quaternary centres with acute myocardial infarction (MI). Over 1.4 million participants from 18 studies, including primary prospective, cross sectional and retrospective observational studies, as well as secondary analysis of registry data are included in the study. The study showed that women were more likely than men to have a previous diagnosis of diabetes, hypertension, cerebrovascular disease, and heart failure. They also had lower odds of presenting with previous ischaemic heart disease and angina, dyslipidaemia, or a smoking history. Further work is necessary to understand the reasons for these differences, and the role that gender-specific risk factors may have in this context. Moreover, how these between-gender differences are implicated in management and outcomes also requires further work. |
| first_indexed | 2024-03-11T00:23:34Z |
| format | Article |
| id | doaj.art-8a78857292ce4fd5a7788306ccf8cbec |
| institution | Directory Open Access Journal |
| issn | 2077-0383 |
| language | English |
| last_indexed | 2024-03-11T00:23:34Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Clinical Medicine |
| spelling | doaj.art-8a78857292ce4fd5a7788306ccf8cbec2023-11-18T23:10:12ZengMDPI AGJournal of Clinical Medicine2077-03832023-08-011215516310.3390/jcm12155163Between-Sex Differences in Risk Factors for Cardiovascular Disease among Patients with Myocardial Infarction—A Systematic ReviewJack Charles Barton0Anna Wozniak1Chloe Scott2Abhisekh Chatterjee3Greg Nathan Titterton4Amber Elyse Corrigan5Ashvin Kuri6Viraj Shah7Ian Soh8Juan Carlos Kaski9Critical Care and Perioperative Medicine Research Group, William Harvey Research Institute, Queen Mary University of London, London E1 4NS, UKCritical Care and Perioperative Medicine Research Group, William Harvey Research Institute, Queen Mary University of London, London E1 4NS, UKCritical Care and Perioperative Medicine Research Group, William Harvey Research Institute, Queen Mary University of London, London E1 4NS, UKDepartment of Medicine, Faculty of Medicine, Imperial College London, London SW7 2AZ, UKBarts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 4NS, UKDepartment of Medicine, Kings College London, London SE5 9RS, UKBarts and the London School of Medicine and Dentistry, Queen Mary University of London, London E1 4NS, UKDepartment of Medicine, Faculty of Medicine, Imperial College London, London SW7 2AZ, UKSt. George’s University of London, London SW17 0RE, UKMolecular and Clinical Sciences Research Institute, St. George’s University of London, London SW17 0RE, UKBetween-sex differences in the presentation, risk factors, management, and outcomes of acute myocardial infarction (MI) are well documented. However, as such differences are highly sensitive to cultural and social changes, there is a need to continuously re-evaluate the evidence. The present contemporary systematic review assesses the baseline characteristics of men and women presenting to secondary, tertiary, and quaternary centres with acute myocardial infarction (MI). Over 1.4 million participants from 18 studies, including primary prospective, cross sectional and retrospective observational studies, as well as secondary analysis of registry data are included in the study. The study showed that women were more likely than men to have a previous diagnosis of diabetes, hypertension, cerebrovascular disease, and heart failure. They also had lower odds of presenting with previous ischaemic heart disease and angina, dyslipidaemia, or a smoking history. Further work is necessary to understand the reasons for these differences, and the role that gender-specific risk factors may have in this context. Moreover, how these between-gender differences are implicated in management and outcomes also requires further work.https://www.mdpi.com/2077-0383/12/15/5163risk factorsmyocardial infarctionsexgenderwomen |
| spellingShingle | Jack Charles Barton Anna Wozniak Chloe Scott Abhisekh Chatterjee Greg Nathan Titterton Amber Elyse Corrigan Ashvin Kuri Viraj Shah Ian Soh Juan Carlos Kaski Between-Sex Differences in Risk Factors for Cardiovascular Disease among Patients with Myocardial Infarction—A Systematic Review Journal of Clinical Medicine risk factors myocardial infarction sex gender women |
| title | Between-Sex Differences in Risk Factors for Cardiovascular Disease among Patients with Myocardial Infarction—A Systematic Review |
| title_full | Between-Sex Differences in Risk Factors for Cardiovascular Disease among Patients with Myocardial Infarction—A Systematic Review |
| title_fullStr | Between-Sex Differences in Risk Factors for Cardiovascular Disease among Patients with Myocardial Infarction—A Systematic Review |
| title_full_unstemmed | Between-Sex Differences in Risk Factors for Cardiovascular Disease among Patients with Myocardial Infarction—A Systematic Review |
| title_short | Between-Sex Differences in Risk Factors for Cardiovascular Disease among Patients with Myocardial Infarction—A Systematic Review |
| title_sort | between sex differences in risk factors for cardiovascular disease among patients with myocardial infarction a systematic review |
| topic | risk factors myocardial infarction sex gender women |
| url | https://www.mdpi.com/2077-0383/12/15/5163 |
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