Viral hepatitis E: Clinical manifestations, treatment, and prevention

Hepatitis E is a globally distributed infection that varies in seroprevalence between developed and developing regions. In the less developed regions of Asia and Africa, a high seropositivity rate has been reported for hepatitis E virus (HEV) antibodies. Although acute hepatitis E is often self-limi...

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Bibliographic Details
Main Authors: Qiumin Luo, Jia Chen, Yeqiong Zhang, Wenxiong Xu, Ying Liu, Chan Xie, Liang Peng
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-03-01
Series:Liver Research
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Online Access:http://www.sciencedirect.com/science/article/pii/S2542568424000011
Description
Summary:Hepatitis E is a globally distributed infection that varies in seroprevalence between developed and developing regions. In the less developed regions of Asia and Africa, a high seropositivity rate has been reported for hepatitis E virus (HEV) antibodies. Although acute hepatitis E is often self-limited and has a favorable prognosis, some populations experience severe manifestations, which may progress to liver failure. Moreover, some immunocompromised patients are at risk of developing chronic HEV infection and cirrhosis. Proactive screening, reducing misdiagnosis, improving patient management, timely antiviral therapy for severe and chronic cases, and vaccination of high-risk groups are important measures to reduce the morbidity of hepatitis E. This review focused on the clinical presentation, management, and prevention of hepatitis E.
ISSN:2542-5684