Pteridines, LXXXVIII. Oxidations and Reactions of 2- and 4-Thiolumazine Derivatives. Synthesis and Properties of Pteridine-Sulfinates and -sulfonates
Selective oxidations of 2-thiolumazines (10-12) by H20 2 and KMn04 respectively in basic medium led to the corresponding stable pteridin-4-one-2-sulfinates (13-15) and -sulfonates (16-18), which can be isolated in the form of their potassium salts. On oxidation of 6,7-diphenyl-2-thiolumazine (12) wi...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
De Gruyter
1989-02-01
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| Series: | Pteridines |
| Online Access: | https://doi.org/10.1515/pteridines.1989.1.1.45 |
| Summary: | Selective oxidations of 2-thiolumazines (10-12) by H20 2 and KMn04 respectively in basic medium led to the corresponding stable pteridin-4-one-2-sulfinates (13-15) and -sulfonates (16-18), which can be isolated in the form of their potassium salts. On oxidation of 6,7-diphenyl-2-thiolumazine (12) with 1 equivalent of H20 2 resulted the 6,7-diphenyl-pteridin-4-one-2-sulfenate (22), which is regarded as an intermediate in the formation of the sulfinates. Characterization was done by elemental analysis, pKa determination, and UV-, IR- and IH-NMR-spectra. |
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| ISSN: | 0933-4807 2195-4720 |