C-Reactive Protein As a Mediator of Complement Activation and Inflammatory Signaling in Age-Related Macular Degeneration

C-Reactive Protein As a Mediator of Complement Activation and Inflammatory Signaling in Age-Related Macular Degeneration

Age-related macular degeneration (AMD) is a devastating neurodegenerative disease affecting millions worldwide. Complement activation, inflammation, and the loss of choroidal endothelial cells have been established as key factors in both normal aging and AMD; however, the exact mechanisms for these...

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Bibliographic Details
Main Authors:	Kathleen R. Chirco, Lawrence A. Potempa
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-03-01
Series:	Frontiers in Immunology
Subjects:	C-reactive protein age-related macular degeneration inflammation complement complement factor H membrane attack complex
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.00539/full

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