Temporal Control of the WNT Signaling Pathway During Cardiac Differentiation Impacts Upon the Maturation State of Human Pluripotent Stem Cell Derived Cardiomyocytes

Temporal Control of the WNT Signaling Pathway During Cardiac Differentiation Impacts Upon the Maturation State of Human Pluripotent Stem Cell Derived Cardiomyocytes

Inefficient differentiation and insufficient maturation are barriers to the application of human pluripotent stem cell (hPSC)-derived cardiomyocytes (CMs) for research and therapy. Great strides have been made to the former, and multiple groups have reported cardiac differentiation protocol that can...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Chantelle Tsoi, Ruixia Deng, Maxwell Kwok, Bin Yan, Carrie Lee, Hung Sing Li, Chloe Ho Yi Ma, Ruibang Luo, Kam Tong Leung, Godfrey Chi-Fung Chan, Larry Ming-cheung Chow, Ellen N. Poon
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: Frontiers Media S.A. 2022-03-01
Σειρά:Frontiers in Molecular Biosciences
Θέματα:
hPSC-CMs
cardiac maturation
cardiac differentiation
mitochondria
human pluripotent stem cell derived cardiomyocytes
wnt signalling pathway
Διαθέσιμο Online:https://www.frontiersin.org/articles/10.3389/fmolb.2022.714008/full

Διαδίκτυο

https://www.frontiersin.org/articles/10.3389/fmolb.2022.714008/full

Παρόμοια τεκμήρια