Evaluation of insulin resistance and vitamin D levels in patients with polycystic ovary syndrome

Background: Polycystic ovary syndrome (PCOS) is associated with many long term health problems such as increased risk of obesity, type 2 diabetes, metabolic syndrome and cardiovascular risk factors. Several reports indicated that PCOS patients have lower vitamin D status compared to healthy subjects...

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Main Authors: Pınar Şişman, Soner Cander, Özen Öz Gül
Format: Article
Language:English
Published: Nizameddin KOCA 2023-01-01
Series:Turkish Journal of Internal Medicine
Subjects:
Online Access:https://dergipark.org.tr/tr/download/article-file/2094234
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author Pınar Şişman
Soner Cander
Özen Öz Gül
author_facet Pınar Şişman
Soner Cander
Özen Öz Gül
author_sort Pınar Şişman
collection DOAJ
description Background: Polycystic ovary syndrome (PCOS) is associated with many long term health problems such as increased risk of obesity, type 2 diabetes, metabolic syndrome and cardiovascular risk factors. Several reports indicated that PCOS patients have lower vitamin D status compared to healthy subjects. In our study we aimed to investigate whether vitamin D deficiency has effect on the pathogenesis of insulin resistance in PCOS. Material and Methods: Fourty eight patients with PCOS and 24 healthy controls were included in the study. Following the physical examination and anthropometric measurements of the patients and healthy subjects, glycemic control data, lipid values, parathormone, vitamin D status and hormonal parameters were studied. Results: In our study, vitamin D levels were significantly lower in PCOS patients (19.7±26.9 ng/mL) compared with controls (31.9±35 ng/mL, p
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spelling doaj.art-8a82d4b0a09b46a48c4d09186542272d2023-02-15T16:13:37ZengNizameddin KOCATurkish Journal of Internal Medicine2687-42452023-01-010010.46310/tjim.10270191881Evaluation of insulin resistance and vitamin D levels in patients with polycystic ovary syndromePınar Şişman0Soner Cander1Özen Öz Gül2Medicana Bursa HospitalBURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, TIP PR.BURSA ULUDAĞ ÜNİVERSİTESİ, TIP FAKÜLTESİ, TIP PR.Background: Polycystic ovary syndrome (PCOS) is associated with many long term health problems such as increased risk of obesity, type 2 diabetes, metabolic syndrome and cardiovascular risk factors. Several reports indicated that PCOS patients have lower vitamin D status compared to healthy subjects. In our study we aimed to investigate whether vitamin D deficiency has effect on the pathogenesis of insulin resistance in PCOS. Material and Methods: Fourty eight patients with PCOS and 24 healthy controls were included in the study. Following the physical examination and anthropometric measurements of the patients and healthy subjects, glycemic control data, lipid values, parathormone, vitamin D status and hormonal parameters were studied. Results: In our study, vitamin D levels were significantly lower in PCOS patients (19.7±26.9 ng/mL) compared with controls (31.9±35 ng/mL, phttps://dergipark.org.tr/tr/download/article-file/2094234polycyctic ovary syndromevitamin d levelsobesityinsulin resistance
spellingShingle Pınar Şişman
Soner Cander
Özen Öz Gül
Evaluation of insulin resistance and vitamin D levels in patients with polycystic ovary syndrome
Turkish Journal of Internal Medicine
polycyctic ovary syndrome
vitamin d levels
obesity
insulin resistance
title Evaluation of insulin resistance and vitamin D levels in patients with polycystic ovary syndrome
title_full Evaluation of insulin resistance and vitamin D levels in patients with polycystic ovary syndrome
title_fullStr Evaluation of insulin resistance and vitamin D levels in patients with polycystic ovary syndrome
title_full_unstemmed Evaluation of insulin resistance and vitamin D levels in patients with polycystic ovary syndrome
title_short Evaluation of insulin resistance and vitamin D levels in patients with polycystic ovary syndrome
title_sort evaluation of insulin resistance and vitamin d levels in patients with polycystic ovary syndrome
topic polycyctic ovary syndrome
vitamin d levels
obesity
insulin resistance
url https://dergipark.org.tr/tr/download/article-file/2094234
work_keys_str_mv AT pınarsisman evaluationofinsulinresistanceandvitamindlevelsinpatientswithpolycysticovarysyndrome
AT sonercander evaluationofinsulinresistanceandvitamindlevelsinpatientswithpolycysticovarysyndrome
AT ozenozgul evaluationofinsulinresistanceandvitamindlevelsinpatientswithpolycysticovarysyndrome