A Review: Halogenated Compounds from Marine Fungi
Marine fungi produce many halogenated metabolites with a variety of structures, from acyclic entities with a simple linear chain to multifaceted polycyclic molecules. Over the past few decades, their pharmaceutical and medical application have been explored and still the door is kept open due to the...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-01-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/26/2/458 |
| _version_ | 1827600293048614912 |
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| author | Cong Wang Huanyun Lu Jianzhou Lan KH Ahammad Zaman Shugeng Cao |
| author_facet | Cong Wang Huanyun Lu Jianzhou Lan KH Ahammad Zaman Shugeng Cao |
| author_sort | Cong Wang |
| collection | DOAJ |
| description | Marine fungi produce many halogenated metabolites with a variety of structures, from acyclic entities with a simple linear chain to multifaceted polycyclic molecules. Over the past few decades, their pharmaceutical and medical application have been explored and still the door is kept open due to the need of new drugs from relatively underexplored sources. Biological properties of halogenated compounds such as anticancer, antiviral, antibacterial, anti-inflammatory, antifungal, antifouling, and insecticidal activity have been investigated. This review describes the chemical structures and biological activities of 217 halogenated compounds derived mainly from <i>Penicillium</i> and <i>Aspergillus</i> marine fungal strains reported from 1994 to 2019. |
| first_indexed | 2024-03-09T04:33:04Z |
| format | Article |
| id | doaj.art-8a897633fdaa4a39b03d5fe5c874c737 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-09T04:33:04Z |
| publishDate | 2021-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-8a897633fdaa4a39b03d5fe5c874c7372023-12-03T13:32:36ZengMDPI AGMolecules1420-30492021-01-0126245810.3390/molecules26020458A Review: Halogenated Compounds from Marine FungiCong Wang0Huanyun Lu1Jianzhou Lan2KH Ahammad Zaman3Shugeng Cao4Key Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, School of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Nanning 530006, ChinaKey Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, School of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Nanning 530006, ChinaKey Laboratory of Chemistry and Engineering of Forest Products, State Ethnic Affairs Commission, Guangxi Key Laboratory of Chemistry and Engineering of Forest Products, Guangxi Collaborative Innovation Center for Chemistry and Engineering of Forest Products, School of Chemistry and Chemical Engineering, Guangxi University for Nationalities, Nanning 530006, ChinaDepartment of Pharmaceutical Sciences, Daniel K. Inouye College of Pharmacy, University of Hawai’i, Hilo, HI 96720, USADepartment of Pharmaceutical Sciences, Daniel K. Inouye College of Pharmacy, University of Hawai’i, Hilo, HI 96720, USAMarine fungi produce many halogenated metabolites with a variety of structures, from acyclic entities with a simple linear chain to multifaceted polycyclic molecules. Over the past few decades, their pharmaceutical and medical application have been explored and still the door is kept open due to the need of new drugs from relatively underexplored sources. Biological properties of halogenated compounds such as anticancer, antiviral, antibacterial, anti-inflammatory, antifungal, antifouling, and insecticidal activity have been investigated. This review describes the chemical structures and biological activities of 217 halogenated compounds derived mainly from <i>Penicillium</i> and <i>Aspergillus</i> marine fungal strains reported from 1994 to 2019.https://www.mdpi.com/1420-3049/26/2/458marine fungichemical structuresnatural productshalogenated compounds |
| spellingShingle | Cong Wang Huanyun Lu Jianzhou Lan KH Ahammad Zaman Shugeng Cao A Review: Halogenated Compounds from Marine Fungi Molecules marine fungi chemical structures natural products halogenated compounds |
| title | A Review: Halogenated Compounds from Marine Fungi |
| title_full | A Review: Halogenated Compounds from Marine Fungi |
| title_fullStr | A Review: Halogenated Compounds from Marine Fungi |
| title_full_unstemmed | A Review: Halogenated Compounds from Marine Fungi |
| title_short | A Review: Halogenated Compounds from Marine Fungi |
| title_sort | review halogenated compounds from marine fungi |
| topic | marine fungi chemical structures natural products halogenated compounds |
| url | https://www.mdpi.com/1420-3049/26/2/458 |
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