Monocarboxylate Transporter 1 May Benefit Cerebral Ischemia via Facilitating Lactate Transport From Glial Cells to Neurons

Monocarboxylate Transporter 1 May Benefit Cerebral Ischemia via Facilitating Lactate Transport From Glial Cells to Neurons

Monocarboxylate transporter 1 (MCT1) is expressed in glial cells and some populations of neurons. MCT1 facilitates astrocytes or oligodendrocytes (OLs) in the energy supplement of neurons, which is crucial for maintaining the neuronal activity and axonal function. It is suggested that MCT1 upregulat...

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Bibliographic Details
Main Authors: Mao Zhang, Yanyan Wang, Yun Bai, Limeng Dai, Hong Guo
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Neurology
Subjects:
monocarboxylate transporter 1 (MCT1)
lactate transport
cerebral ischemia
astrocytes
oligodendrocytes (OLs)
Online Access:https://www.frontiersin.org/articles/10.3389/fneur.2022.781063/full

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